Entries tagged Aging, Premature/genetics/metabolism/pathology (187)

  1130: Greenbaum et al. (1998) "CCAAT enhancer- binding protein beta is required for normal hepatocyte proliferation in mice after partial hepatectomy." J. Clin. Invest. 102(5):996-991007 (PubMed)

  3784: Zhu et al. (1998) "Senescence of human fibroblasts induced by oncogenic Raf." Genes Dev. 12(19):2997-3007 (PubMed)

  3785: Atadja et al. (1995) "Overexpression of cyclin D1 blocks proliferation of normal diploid fibroblasts." Exp. Cell Res. 217(2):205-216 (PubMed)

  3796: Serrano et al. (1997) "Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a." Cell 88(5):593-602 (PubMed)

  3806: Park et al. (2010) "Loss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1." J. Cell. Sci. 123(Pt 4):619-626 (PubMed)

  3809: Byrne et al. (2010) "Knockdown of human deubiquitinase PSMD14 induces cell cycle arrest and senescence." Exp. Cell Res. 316(2):258-271 (PubMed)

  3814: Santarosa et al. (2009) "Premature senescence is a major response to DNA cross-linking agents in BRCA1-defective cells: implication for tailored treatments of BRCA1 mutation carriers." Mol. Cancer Ther. 8(4):844-854 (PubMed)

  3826: Widodo et al. (2007) "Stress chaperones, mortalin, and pex19p mediate 5-aza-2' deoxycytidine-induced senescence of cancer cells by DNA methylation-independent pathway." J. Gerontol. A Biol. Sci. Med. Sci. 62(3):246-255 (PubMed)

  3837: Fuxe et al. (2000) "Adenovirus-mediated overexpression of p15INK4B inhibits human glioma cell growth, induces replicative senescence, and inhibits telomerase activity similarly to p16INK4A." Cell Growth Differ. 11(7):373-384 (PubMed)

  3995: Honda et al. (2010) "Trehalose extends longevity in the nematode Caenorhabditis elegans." Aging Cell 9(4):558-569 (PubMed)

  4029: Liao et al. (2011) "Curcumin-mediated lifespan extension in Caenorhabditis elegans." Mech. Ageing Dev. 132(10):480-487 (PubMed)

  4151: Weimer et al. (2014) "D-Glucosamine supplementation extends life span of nematodes and of ageing mice." Nat Commun 5:3563 (PubMed)

  4619: Shintani et al. (2017) "d-Allulose, a stereoisomer of d-fructose, extends Caenorhabditis elegans lifespan through a dietary restriction mechanism: A new candidate dietary restriction mimetic." Biochem. Biophys. Res. Commun. 493(4):1528-1533 (PubMed)

  686: Joza et al. (2001) "Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death." Nature 410(6828):549-554 (PubMed)

  723: Fujita et al. (1999) "Expression and structure of senescence marker protein-30 (SMP30) and its biological significance." Mech. Ageing Dev. 107(3):271-280 (PubMed)

  1642: Orellana et al. (2005) "Role of the JAKs/STATs pathway in the intracellular calcium changes induced by interleukin-6 in hippocampal neurons." Neurotox Res 8(3-4):295-304 (PubMed)

  1644: Colotti et al. (2005) "Effects of aging and anti-aging caloric restrictions on carbonyl and heat shock protein levels and expression." Biogerontology 6(6):397-406 (PubMed)

  1694: Silva et al. (2005) "SOD2 overexpression: enhanced mitochondrial tolerance but absence of effect on UCP activity." EMBO J. 24(23):4061-4070 (PubMed)

  1697: Maraganore et al. (2004) "UCHL1 is a Parkinson's disease susceptibility gene." Ann. Neurol. 55(4):512-521 (PubMed)

  1816: Schindowski et al. (2006) "Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits." Am. J. Pathol. 169(2):599-616 (PubMed)