Entries tagged Growth Hormone/antagonists & inhibitors/genetics (954)

  1727: Egan et al. (2003) "The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function." Cell 112(2):257-269 (PubMed)

  1729: Rudolph et al. (1998) "Impaired fetal T cell development and perinatal lethality in mice lacking the cAMP response element binding protein." Proc. Natl. Acad. Sci. U.S.A. 95(8):4481-4486 (PubMed)

  1746: Cai et al. (2004) "IKKbeta/NF-kappaB activation causes severe muscle wasting in mice." Cell 119(2):285-298 (PubMed)

  1763: de Boer et al. (1998) "A mouse model for the basal transcription/DNA repair syndrome trichothiodystrophy." Mol. Cell 1(7):981-990 (PubMed)

  1784: Schieke et al. (2006) "The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity." J. Biol. Chem. 281(37):27643-27652 (PubMed)

  1800: Dahl et al. (2006) "Distinct structural and mechanical properties of the nuclear lamina in Hutchinson-Gilford progeria syndrome." Proc. Natl. Acad. Sci. U.S.A. 103(27):10271-10276 (PubMed)

  1822: Sablina et al. (2005) "The antioxidant function of the p53 tumor suppressor." Nat. Med. 11(12):1306-1313 (PubMed)

  1846: Gerhart-Hines et al. (2007) "Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha." EMBO J. 26(7):1913-1923 (PubMed)

  1860: Chaturvedi et al. (1999) "Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway." Oncogene 18(28):4047-4054 (PubMed)

  1861: Sijbers et al. (1998) "Homozygous R788W point mutation in the XPF gene of a patient with xeroderma pigmentosum and late-onset neurologic disease." J. Invest. Dermatol. 110(5):832-836 (PubMed)

  1868: Gorbacheva et al. (2005) "Circadian sensitivity to the chemotherapeutic agent cyclophosphamide depends on the functional status of the CLOCK/BMAL1 transactivation complex." Proc. Natl. Acad. Sci. U.S.A. 102(9):3407-3412 (PubMed)

  1876: Chen et al. (2003) "Heterozygous disruption of Hic1 predisposes mice to a gender-dependent spectrum of malignant tumors." Nat. Genet. 33(2):197-202 (PubMed)

  1904: Merideth et al. (2008) "Phenotype and course of Hutchinson-Gilford progeria syndrome." N. Engl. J. Med. 358(6):592-604 (PubMed)

  1905: Reddy et al. (2008) "Oocyte-specific deletion of Pten causes premature activation of the primordial follicle pool." Science 319(5863):611-613 (PubMed)

  1942: Holder-Espinasse et al. (2007) "A new mutation in TP63 is associated with age-related pathology." Eur. J. Hum. Genet. 15(11):1115-1120 (PubMed)

  1962: Borgesius et al. (2011) "Accelerated age-related cognitive decline and neurodegeneration, caused by deficient DNA repair." J. Neurosci. 31(35):12543-12553 (PubMed)

  1967: Yao et al. (2012) "SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice." J. Clin. Invest. 122(6):2032-2045 (PubMed)

  1985: Qiang et al. (2010) "Uncoupling of acetylation from phosphorylation regulates FoxO1 function independent of its subcellular localization." J. Biol. Chem. 285(35):27396-27401 (PubMed)

  2023: Gao et al. (2010) "A novel pathway regulates memory and plasticity via SIRT1 and miR-134." Nature 466(7310):1105-1109 (PubMed)

  4196: Huang et al. (2015) "Analysis of lifespan-promoting effect of garlic extract by an integrated metabolo-proteomics approach." J. Nutr. Biochem. 26(8):808-817 (PubMed)