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Entries tagged Bone Marrow Cells/metabolism/radiation effects (165)

3945: McColl et al. (2008) "Pharmacogenetic analysis of lithium-induced delayed aging in Caenorhabditis elegans." J. Biol. Chem. 283(1):350-357 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Humans
- Immunohistochemistry
- Survival Analysis
- Electrophoresis, Polyacrylamide Gel
- Oligonucleotide Array Sequence Analysis
- RNA Interference
- Caenorhabditis elegans Proteins/genetics/metabolism
- Aging/drug effects
- Cell Line, Tumor
- Longevity/drug effects/genetics
- Lithium Chloride/pharmacology
- Glycogen Synthase Kinase 3/genetics/metabolism
- Caenorhabditis elegans/drug effects/genetics/growth & development
- Gene Expression Regulation, Developmental/drug effects
- Genome, Helminth
3954: Wiegant et al. (2009) "Plant adaptogens increase lifespan and stress resistance in C. elegans." Biogerontology 10(1):27-42 (PubMed)

2 citations in connected databases
- Tags:
- Animals
- Ultraviolet Rays
- Forkhead Transcription Factors
- Mutation
- Dose-Response Relationship, Drug
- Transcription Factors/metabolism
- Heat-Shock Proteins/metabolism
- Time Factors
- Caenorhabditis elegans Proteins/genetics/metabolism
- Hot Temperature
- Paraquat/toxicity
- Oxidative Stress/drug effects
- Succinate Dehydrogenase/genetics/metabolism
- Rhodiola
- Plant Extracts/pharmacology
- Caenorhabditis elegans/drug effects/genetics/metabolism/radiation effects
- Eleutherococcus
- Longevity/drug effects/radiation effects
- Plant Roots
- Stress, Physiological/drug effects/radiation effects
3987: Yu et al. (2010) "Cinnamomum cassia bark in two herbal formulas increases life span in Caenorhabditis elegans via insulin signaling and stress response pathways." PLoS ONE 5(2):e9339 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Humans
- Animals, Genetically Modified
- Hydrogen Peroxide/metabolism
- Time Factors
- Models, Animal
- Microscopy, Fluorescence
- Caenorhabditis elegans Proteins/genetics/metabolism
- Aging/drug effects
- Longevity/drug effects
- Caenorhabditis elegans/genetics/metabolism/physiology
- Signal Transduction/drug effects
- Receptor, Insulin/physiology
- Heat-Shock Proteins/genetics/metabolism
- Amyloid beta-Peptides/genetics/metabolism
- Oxidative Stress/drug effects/physiology
- Green Fluorescent Proteins/genetics/metabolism
- Drugs, Chinese Herbal/pharmacology
- Cinnamomum aromaticum/chemistry
- Heat-Shock Proteins, Small/metabolism
- Paralysis/genetics/metabolism/prevention & control
- Plant Bark/chemistry
3996: Bartholome et al. (2010) "Epigallocatechin gallate-induced modulation of FoxO signaling in mammalian cells and C. elegans: FoxO stimulation is masked via PI3K/Akt activation by hydrogen peroxide formed in cell culture." Arch. Biochem. Biophys. 501(1):58-64 (PubMed)

2 citations in connected databases
- Tags:
- Animals
- Humans
- Phosphorylation
- Cell Line
- Phosphatidylinositol 3-Kinases/metabolism
- Animals, Genetically Modified
- Superoxide Dismutase/genetics/metabolism
- Transcription Factors/metabolism
- Hydrogen Peroxide/metabolism
- Caenorhabditis elegans Proteins/genetics/metabolism
- Longevity/drug effects
- Signal Transduction/drug effects
- Protein-Tyrosine Kinases/antagonists & inhibitors
- Gene Expression/drug effects
- Forkhead Transcription Factors/metabolism
- Proto-Oncogene Proteins c-akt/metabolism
- Caenorhabditis elegans/drug effects/genetics/metabolism
- Catechin/analogs & derivatives/pharmacology
- Genes, Helminth/drug effects
- Harmine/pharmacology
- Protein-Serine-Threonine Kinases/antagonists & inhibitors
4032: Zhang et al. (2012) "Inhibition of polyglutamine-mediated proteotoxicity by Astragalus membranaceus polysaccharide through the DAF-16/FOXO transcription factor in Caenorhabditis elegans." Biochem. J. 441(1):417-424 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Transcription Factors/genetics/metabolism
- Cell Survival
- Caenorhabditis elegans Proteins/genetics/metabolism
- Gene Expression Regulation/drug effects
- Oxidative Stress/drug effects
- Neurons/drug effects
- Forkhead Transcription Factors/genetics/metabolism
- Peptides/metabolism
- Astragalus membranaceus/chemistry
- Endoplasmic Reticulum
- Polysaccharides/chemistry/pharmacology
4088: Huang et al. (2013) "DhHP-6 extends lifespan of Caenorhabditis elegans by enhancing nuclear translocation and transcriptional activity of DAF-16." Free Radic. Res. 47(4):316-324 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Forkhead Transcription Factors
- Transcription Factors/genetics/metabolism
- Aging/genetics/physiology
- Caenorhabditis elegans/genetics/physiology
- Caenorhabditis elegans Proteins/genetics/metabolism
- Sirtuins/metabolism
- Longevity/drug effects
- Signal Transduction/drug effects
- Oxidative Stress/drug effects
- Cell Nucleus/genetics/metabolism
- Hemin/administration & dosage/analogs & derivatives
- Oligopeptides/administration & dosage
4089: O'Rourke et al. (2013) "ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy." Genes Dev. 27(4):429-440 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Humans
- Mice
- Longevity/physiology
- Cell Line
- HeLa Cells
- Survival Analysis
- Gene Expression Regulation
- Caenorhabditis elegans Proteins/genetics/metabolism
- Caenorhabditis elegans/metabolism/physiology
- Lipolysis
- Fasting/physiology
- Autophagy/physiology
- Lipase/genetics/metabolism
- Fatty Acids, Omega-6/metabolism
4544: Tauffenberger et al. (2016) "Fragile lifespan expansion by dietary mitohormesis in C. elegans." Aging (Albany NY) 8(1):50-61 (PubMed)

9 citations in connected databases
- Tags:
- Animals
- Genotype
- Oxidative Stress
- Antioxidants/pharmacology
- Phenotype
- Age Factors
- Caenorhabditis elegans Proteins/genetics/metabolism
- Longevity/drug effects
- Protein Folding
- Mitochondria/drug effects/metabolism
- Mitochondrial Proteins/genetics/metabolism
- Caenorhabditis elegans/drug effects/genetics/metabolism
- Dietary Carbohydrates/metabolism/toxicity
- Glucose/metabolism/toxicity
- Unfolded Protein Response/drug effects/genetics
4554: Anderson et al. (2016) "C. elegans lifespan extension by osmotic stress requires FUdR, base excision repair, FOXO, and sirtuins." Mech. Ageing Dev. 154:30-42 (PubMed)

6 citations in connected databases
- Tags:
- Animals
- DNA Repair/drug effects
- Sirtuins/genetics/metabolism
- Caenorhabditis elegans Proteins/genetics/metabolism
- Longevity/drug effects
- Caenorhabditis elegans/genetics/metabolism
- Forkhead Transcription Factors/genetics/metabolism
- Floxuridine/pharmacology
- Osmotic Pressure/drug effects
4650: Shen et al. (2017) "Piceatannol extends the lifespan of Caenorhabditis elegans via DAF-16." Biofactors 43(3):379-387 (PubMed)

2 citations in connected databases
- Tags:
- Animals
- Humans
- Oxidative Stress
- Signal Transduction
- Antioxidants/pharmacology
- Gene Expression Regulation
- Gene Expression Profiling
- Stress, Physiological/genetics
- Caenorhabditis elegans Proteins/genetics/metabolism
- Caenorhabditis elegans/genetics/growth & development/metabolism
- Hot Temperature
- Stilbenes/pharmacology
- Adaptation, Physiological/genetics
- Longevity/drug effects/genetics
- Forkhead Transcription Factors/genetics/metabolism
- Locomotion/drug effects/physiology
- Reactive Oxygen Species/antagonists & inhibitors/metabolism
4688: Nguyen et al. (2016) "Scavengers of reactive γ-ketoaldehydes extend Caenorhabditis elegans lifespan and healthspan through protein-level interactions with SIR-2.1 and ETS-7." Aging (Albany NY) 8(8):1759-1780 (PubMed)

2 citations in connected databases
- Tags:
- Animals
- Longevity/physiology
- Aging/physiology
- Animals, Genetically Modified
- Sirtuins/genetics/metabolism
- Caenorhabditis elegans Proteins/genetics/metabolism
- Caenorhabditis elegans/metabolism
- Lipid Peroxidation/physiology
- Proto-Oncogene Proteins c-ets/genetics/metabolism
1674: Awata et al. (2002) "A common polymorphism in the 5'-untranslated region of the VEGF gene is associated with diabetic retinopathy in type 2 diabetes." Diabetes 51(5):1635-1639 (PubMed)

1 citation in connected databases
- Tags:
- Humans
- Female
- Genotype
- Male
- Adult
- Adolescent
- Middle Aged
- Linkage Disequilibrium
- Polymorphism, Genetic
- Aged
- Aged, 80 and over
- Vascular Endothelial Growth Factor A
- Vascular Endothelial Growth Factors
- 5' Untranslated Regions/genetics
- Diabetes Mellitus, Type 2/genetics
- Diabetic Retinopathy/blood/genetics
- Endothelial Growth Factors/blood/genetics
- Lymphokines/blood/genetics
427: Kung et al. (2000) "Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP." Genes Dev. 14(3):272-277 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Mice
- Mice, Knockout
- Mice, Inbred C57BL
- Heterozygote
- Phenotype
- Blotting, Western
- Blotting, Southern
- CREB-Binding Protein
- Spleen/cytology
- Bone Marrow Transplantation
- Hematopoiesis/genetics
- Genes, Tumor Suppressor/genetics
- E1A-Associated p300 Protein
- Nuclear Proteins/genetics/metabolism
- Trans-Activators/genetics/metabolism
- Cell Transplantation
- Hematologic Neoplasms/genetics/pathology
- Loss of Heterozygosity
3281: Alam et al. (2010) "EAK-7 controls development and life span by regulating nuclear DAF-16/FoxO activity." Cell Metab. 12(1):30-41 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Carrier Proteins/genetics/metabolism
- Longevity
- Mutation
- Transcription Factors/metabolism
- RNA Interference
- Caenorhabditis elegans Proteins/genetics/metabolism
- Caenorhabditis elegans
- Forkhead Transcription Factors/metabolism
- Proto-Oncogene Proteins c-akt/genetics/metabolism
3397: Menthena et al. (2011) "Activin A, p15INK4b signaling, and cell competition promote stem/progenitor cell repopulation of livers in aging rats." Gastroenterology 140(3):1009-1020 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Apoptosis
- Signal Transduction
- Cells, Cultured
- Rats
- Immunohistochemistry
- RNA, Messenger/metabolism
- Age Factors
- Reverse Transcriptase Polymerase Chain Reaction
- Blotting, Western
- In Situ Nick-End Labeling
- Aging/metabolism/pathology
- Rats, Inbred F344
- Cyclin-Dependent Kinases/metabolism
- Cyclins/metabolism
- Liver Regeneration
- Cell Proliferation
- Hepatocytes/metabolism/pathology
- Cyclin-Dependent Kinase Inhibitor p15/genetics/metabolism
- Dipeptidyl Peptidase 4/deficiency/genetics
- Fetal Stem Cells/metabolism/transplantation
- Inhibin-beta Subunits/genetics/metabolism
- Ki-67 Antigen/metabolism
- Liver/embryology/metabolism/pathology
- Rats, Transgenic
2234: Viswanathan et al. (2005) "A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span." Dev. Cell 9(5):605-615 (PubMed)

4 citations in connected databases
- Tags:
- Animals
- Fungal Proteins/metabolism
- Gene Expression Profiling
- Caenorhabditis elegans Proteins/genetics/metabolism
- Sirtuins/metabolism
- Heat-Shock Proteins/genetics/metabolism
- Stilbenes/pharmacology
- Longevity/drug effects/genetics
- Caenorhabditis elegans/drug effects/genetics/physiology
- Asparagine/chemistry
- Endoplasmic Reticulum/drug effects/genetics/metabolism
- Glutamine/chemistry
- RNA Interference/drug effects/physiology
- Transcription, Genetic/drug effects/genetics
2238: Powers et al. (2006) "Extension of chronological life span in yeast by decreased TOR pathway signaling." Genes Dev. 20(2):174-184 (PubMed)

6 citations in connected databases
- Tags:
- Gene Deletion
- Longevity
- Mutation
- Protein-Serine-Threonine Kinases
- Transcription Factors/genetics/metabolism
- Phenotype
- Gene Expression Regulation, Fungal
- Oxidative Stress/genetics/physiology
- Conserved Sequence
- DNA-Binding Proteins/metabolism
- Signal Transduction/genetics/physiology
- Hot Temperature
- Repressor Proteins/genetics
- Nuclear Localization Signals/metabolism
- Sequence Homology
- Saccharomyces cerevisiae/genetics/metabolism/physiology
- Amino Acids/metabolism
- Saccharomyces cerevisiae Proteins/antagonists & inhibitors/genetics/metabolism
2292: Van Gilst et al. (2005) "Nuclear hormone receptor NHR-49 controls fat consumption and fatty acid composition in C. elegans." PLoS Biol. 3(2):e53 (PubMed)

2 citations in connected databases
- Tags:
- Animals
- Caenorhabditis elegans Proteins/genetics/metabolism
- Caenorhabditis elegans/genetics/metabolism
- Energy Metabolism/genetics
- Mitochondria/genetics/metabolism
- Fatty Acids/chemistry/metabolism
- Receptors, Cytoplasmic and Nuclear/chemistry/genetics/metabolism
2425: Ayyadevara et al. (2009) "Caenorhabditis elegans PI3K mutants reveal novel genes underlying exceptional stress resistance and lifespan." Aging Cell 8(6):706-725 (PubMed)

6 citations in connected databases
- Tags:
- Animals
- Longevity
- Mutation
- Alleles
- Transcription, Genetic
- Binding Sites
- Gene Expression Regulation
- Oligonucleotide Array Sequence Analysis
- RNA Interference
- Caenorhabditis elegans Proteins/genetics/metabolism
- Stress, Physiological
- Phosphatidylinositol 3-Kinases/genetics/metabolism
- Caenorhabditis elegans/enzymology/genetics
2430: Son et al. (2011) "DHS-21, a dicarbonyl/L-xylulose reductase (DCXR) ortholog, regulates longevity and reproduction in Caenorhabditis elegans." FEBS Lett. 585(9):1310-1316 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Female
- Male
- Longevity/genetics
- Mutation
- Amino Acid Sequence
- Molecular Sequence Data
- Sequence Homology, Amino Acid
- Kinetics
- Recombinant Proteins/metabolism
- Animals, Genetically Modified
- Blotting, Western
- NADP/metabolism
- Microscopy, Fluorescence
- RNA Interference
- Caenorhabditis elegans Proteins/genetics/metabolism
- Reproduction/genetics
- Green Fluorescent Proteins/genetics/metabolism
- Biocatalysis
- Caenorhabditis elegans/enzymology/genetics/growth & development
- Sugar Alcohol Dehydrogenases/genetics/metabolism
- Xylitol/metabolism
- Xylulose/metabolism