Entries tagged Telomere/metabolism/physiology/ultrastructure (43)

  575: Abel et al. (2001) "Expression of expanded repeat androgen receptor produces neurologic disease in transgenic mice." Hum. Mol. Genet. 10(2):107-116 (PubMed)

  4094: Liu et al. (2013) "Lifespan extension by n-butanol extract from seed of Platycladus orientalis in Caenorhabditis elegans." J Ethnopharmacol 147(2):366-372 (PubMed)

  1067: Goldman et al. (2004) "Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome." Proc. Natl. Acad. Sci. U.S.A. 101(24):8963-8968 (PubMed)

  1417: Brunet et al. (1998) "Noggin, cartilage morphogenesis, and joint formation in the mammalian skeleton." Science 280(5368):1455-1457 (PubMed)

  1597: Babu et al. (2003) "Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation." J. Cell Biol. 160(3):341-353 (PubMed)

  1621: Pastorino et al. (2006) "The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production." Nature 440(7083):528-534 (PubMed)

  1990: Wang et al. (2008) "Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice." Cancer Cell 14(4):312-323 (PubMed)

  674: Ly et al. (2000) "Mitotic misregulation and human aging." Science 287(5462):2486-2492 (PubMed)

  822: Zhang et al. (1996) "Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2." Nature 381(6579):238-241 (PubMed)

  4662: Chattopadhyay et al. (2017) "Hormetic efficacy of rutin to promote longevity in Drosophila melanogaster." Biogerontology 18(3):397-411 (PubMed)

  1115: Csoka et al. (2004) "Genome-scale expression profiling of Hutchinson-Gilford progeria syndrome reveals widespread transcriptional misregulation leading to mesodermal/mesenchymal defects and accelerated atherosclerosis." Aging Cell 3(4):235-243 (PubMed)

  1676: Wooster et al. (1995) "Identification of the breast cancer susceptibility gene BRCA2." Nature 378(6559):789-792 (PubMed)

  24: Bodnar et al. (1998) "Extension of life-span by introduction of telomerase into normal human cells." Science 279(5349):349-352 (PubMed)

  476: Lee et al. (1999) "Mitotic checkpoint inactivation fosters transformation in cells lacking the breast cancer susceptibility gene, Brca2." Mol. Cell 4(1):1-10 (PubMed)

  191: Stefanini et al. (1986) "Xeroderma pigmentosum (complementation group D) mutation is present in patients affected by trichothiodystrophy with photosensitivity." Hum. Genet. 74(2):107-112 (PubMed)

  477: Ludwig et al. (1997) "Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos." Genes Dev. 11(10):1226-1241 (PubMed)

  478: Suzuki et al. (1997) "Brca2 is required for embryonic cellular proliferation in the mouse." Genes Dev. 11(10):1242-1252 (PubMed)

  755: Cummings et al. (2001) "Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice." Hum. Mol. Genet. 10(14):1511-1518 (PubMed)

  1045: Sun et al. (2004) "Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASG." Genes Dev. 18(9):1035-1046 (PubMed)

  1080: Davenport et al. (1999) "The mouse mitotic checkpoint gene bub1b, a novel bub1 family member, is expressed in a cell cycle-dependent manner." Genomics 55(1):113-117 (PubMed)