Entries tagged Oxidoreductases/genetics/physiology (74)

  4671: Papaevgeniou et al. (2016) "18α-Glycyrrhetinic Acid Proteasome Activator Decelerates Aging and Alzheimer's Disease Progression in Caenorhabditis elegans and Neuronal Cultures." Antioxid. Redox Signal. 25(16):855-869 (PubMed)

  3322: Chung et al. (2008) "HSP72 protects against obesity-induced insulin resistance." Proc. Natl. Acad. Sci. U.S.A. 105(5):1739-1744 (PubMed)

  3507: Takahashi et al. (2014) "Extended lifespan, reduced body size and leg skeletal muscle mass, and decreased mitochondrial function in clk-1 transgenic mice." Exp. Gerontol. 58:146-153 (PubMed)

  42: Ruan et al. (2002) "High-quality life extension by the enzyme peptide methionine sulfoxide reductase." Proc. Natl. Acad. Sci. U.S.A. 99(5):2748-2753 (PubMed)

  2741: Jin et al. (2003) "Neurogenesis and aging: FGF-2 and HB-EGF restore neurogenesis in hippocampus and subventricular zone of aged mice." Aging Cell 2(3):175-183 (PubMed)

  2786: Butcher et al. (2000) "Review article: ageing and the neutrophil: no appetite for killing?" Immunology 100(4):411-416 (PubMed)

  798: Bourgeron et al. (1995) "Mutation of a nuclear succinate dehydrogenase gene results in mitochondrial respiratory chain deficiency." Nat. Genet. 11(2):144-149 (PubMed)

  799: Ishii et al. (1998) "A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes." Nature 394(6694):694-697 (PubMed)

  972: Medema et al. (2000) "AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1." Nature 404(6779):782-787 (PubMed)

  215: Bergman et al. (1999) "Upregulation of GFRalpha-1 and c-ret in primary sensory neurons and spinal motoneurons of aged rats." J. Neurosci. Res. 57(2):153-165 (PubMed)

  831: Conover et al. (1995) "Neuronal deficits, not involving motor neurons, in mice lacking BDNF and/or NT4." Nature 375(6528):235-238 (PubMed)

  850: Intano et al. (2002) "Base excision repair is limited by different proteins in male germ cell nuclear extracts prepared from young and old mice." Mol. Cell. Biol. 22(7):2410-2418 (PubMed)

  1582: Chen et al. (2005) "Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses." Cell 123(3):437-448 (PubMed)

  1605: Meier et al. (2006) "trt-1 is the Caenorhabditis elegans catalytic subunit of telomerase." PLoS Genet. 2(2):e18 (PubMed)

  2025: Satoh et al. (2010) "SIRT1 promotes the central adaptive response to diet restriction through activation of the dorsomedial and lateral nuclei of the hypothalamus." J. Neurosci. 30(30):10220-10232 (PubMed)

  2423: Greer et al. (2010) "Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans." Nature 466(7304):383-387 (PubMed)

  2521: de Voer et al. (2005) "Deletion of the Caenorhabditis elegans homologues of the CLN3 gene, involved in human juvenile neuronal ceroid lipofuscinosis, causes a mild progeric phenotype." J. Inherit. Metab. Dis. 28(6):1065-1080 (PubMed)

  2544: Greer et al. (2011) "Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans." Nature 479(7373):365-371 (PubMed)

  2780: Shaker et al. (1993) "Effect of aging and bolus variables on pharyngeal and upper esophageal sphincter motor function." Am. J. Physiol. 264(3 Pt 1):G427-G432 (PubMed)

  3274: van der Goot et al. (2012) "Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation." Proc. Natl. Acad. Sci. U.S.A. 109(37):14912-14917 (PubMed)