Entries tagged Chromosome Disorders (152)

  4553: Abergel et al. (2017) "Synergism between soluble guanylate cyclase signaling and neuropeptides extends lifespan in the nematode Caenorhabditis elegans." Aging Cell 16(2):401-413 (PubMed)

  1476: Agarwal et al. (2003) "Zinc metalloproteinase, ZMPSTE24, is mutated in mandibuloacral dysplasia." Hum. Mol. Genet. 12(16):1995-2001 (PubMed)

  3503: Wang et al. (2015) "miR-124/ATF-6, a novel lifespan extension pathway of Astragalus polysaccharide in Caenorhabditis elegans." J. Cell. Biochem. 116(2):242-251 (PubMed)

  3519: Yizhak et al. (2013) "Model-based identification of drug targets that revert disrupted metabolism and its application to ageing." Nat Commun 4:2632 (PubMed)

  3553: Chondrogianni et al. (2015) "20S proteasome activation promotes life span extension and resistance to proteotoxicity in Caenorhabditis elegans." FASEB J. 29(2):611-622 (PubMed)

  3573: Robida-Stubbs et al. (2012) "TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO." Cell Metab. 15(5):713-724 (PubMed)

  3950: Selman et al. (2008) "Lifelong alpha-tocopherol supplementation increases the median life span of C57BL/6 mice in the cold but has only minor effects on oxidative damage." Rejuvenation Res 11(1):83-96 (PubMed)

  3959: Saul et al. (2008) "Quercetin-mediated longevity in Caenorhabditis elegans: is DAF-16 involved?" Mech. Ageing Dev. 129(10):611-613 (PubMed)

  3960: Benedetti et al. (2008) "Compounds that confer thermal stress resistance and extended lifespan." Exp. Gerontol. 43(10):882-891 (PubMed)

  1073: Cohen et al. (2004) "Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis." Mol. Cell 13(5):627-638 (PubMed)

  1124: Flodby et al. (1996) "Increased hepatic cell proliferation and lung abnormalities in mice deficient in CCAAT/enhancer binding protein alpha." J. Biol. Chem. 271(40):24753-24760 (PubMed)

  1158: You et al. (2004) "p53-dependent inhibition of FKHRL1 in response to DNA damage through protein kinase SGK1." Proc. Natl. Acad. Sci. U.S.A. 101(39):14057-14062 (PubMed)

  1290: van Heemst et al. (2005) "Variation in the human TP53 gene affects old age survival and cancer mortality." Exp. Gerontol. 40(1-2):11-15 (PubMed)

  1496: Fridell et al. (2005) "Targeted expression of the human uncoupling protein 2 (hUCP2) to adult neurons extends life span in the fly." Cell Metab. 1(2):145-152 (PubMed)

  1849: Bonawitz et al. (2007) "Reduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expression." Cell Metab. 5(4):265-277 (PubMed)

  2074: Min et al. (2010) "Acetylation of tau inhibits its degradation and contributes to tauopathy." Neuron 67(6):953-966 (PubMed)

  2212: Kapeta et al. (2010) "Nuclear erythroid factor 2-mediated proteasome activation delays senescence in human fibroblasts." J. Biol. Chem. 285(11):8171-8184 (PubMed)

  2366: Cvejic et al. (2004) "The endogenous ligand Stunted of the GPCR Methuselah extends lifespan in Drosophila." Nat. Cell Biol. 6(6):540-546 (PubMed)

  2408: Bahadorani et al. (2010) "Overexpression of metal-responsive transcription factor (MTF-1) in Drosophila melanogaster ameliorates life-span reductions associated with oxidative stress and metal toxicity." Neurobiol. Aging 31(7):1215-1226 (PubMed)

  622: Matuoka et al. (1993) "Ash/Grb-2, a SH2/SH3-containing protein, couples to signaling for mitogenesis and cytoskeletal reorganization by EGF and PDGF." EMBO J. 12(9):3467-3473 (PubMed)