Entries tagged Lactams, Macrocyclic (80)

  3446: Kaeberlein et al. (2006) "Lifespan extension in Caenorhabditis elegans by complete removal of food." Aging Cell 5(6):487-494 (PubMed)

  3503: Wang et al. (2015) "miR-124/ATF-6, a novel lifespan extension pathway of Astragalus polysaccharide in Caenorhabditis elegans." J. Cell. Biochem. 116(2):242-251 (PubMed)

  3519: Yizhak et al. (2013) "Model-based identification of drug targets that revert disrupted metabolism and its application to ageing." Nat Commun 4:2632 (PubMed)

  3573: Robida-Stubbs et al. (2012) "TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO." Cell Metab. 15(5):713-724 (PubMed)

  3852: Wadhwa et al. (1986) "Life span studies in Zaprionus paravittiger with sodium hypophosphite feeding." Gerontology 32(3):141-147 (PubMed)

  3950: Selman et al. (2008) "Lifelong alpha-tocopherol supplementation increases the median life span of C57BL/6 mice in the cold but has only minor effects on oxidative damage." Rejuvenation Res 11(1):83-96 (PubMed)

  3959: Saul et al. (2008) "Quercetin-mediated longevity in Caenorhabditis elegans: is DAF-16 involved?" Mech. Ageing Dev. 129(10):611-613 (PubMed)

  3960: Benedetti et al. (2008) "Compounds that confer thermal stress resistance and extended lifespan." Exp. Gerontol. 43(10):882-891 (PubMed)

  1849: Bonawitz et al. (2007) "Reduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expression." Cell Metab. 5(4):265-277 (PubMed)

  2177: Greenhalgh et al. (2005) "SOCS2 negatively regulates growth hormone action in vitro and in vivo." J. Clin. Invest. 115(2):397-406 (PubMed)

  2366: Cvejic et al. (2004) "The endogenous ligand Stunted of the GPCR Methuselah extends lifespan in Drosophila." Nat. Cell Biol. 6(6):540-546 (PubMed)

  2408: Bahadorani et al. (2010) "Overexpression of metal-responsive transcription factor (MTF-1) in Drosophila melanogaster ameliorates life-span reductions associated with oxidative stress and metal toxicity." Neurobiol. Aging 31(7):1215-1226 (PubMed)

  301: Cui et al. (2003) "Loss of IGF2 imprinting: a potential marker of colorectal cancer risk." Science 299(5613):1753-1755 (PubMed)

  4523: Huang et al. (2017) "Aspirin increases metabolism through germline signalling to extend the lifespan of Caenorhabditis elegans." PLoS ONE 12(9):e0184027 (PubMed)

  4616: Qi et al. (2017) "The ω-3 fatty acid α-linolenic acid extends Caenorhabditis elegans lifespan via NHR-49/PPARα and oxidation to oxylipins." Aging Cell 16(5):1125-1135 (PubMed)

  2812: Noren Hooten et al. (2010) "microRNA expression patterns reveal differential expression of target genes with age." PLoS ONE 5(5):e10724 (PubMed)

  1115: Csoka et al. (2004) "Genome-scale expression profiling of Hutchinson-Gilford progeria syndrome reveals widespread transcriptional misregulation leading to mesodermal/mesenchymal defects and accelerated atherosclerosis." Aging Cell 3(4):235-243 (PubMed)

  1310: Sun et al. (1997) "Transactivation of Igf2 in a mouse model of Beckwith-Wiedemann syndrome." Nature 389(6653):809-815 (PubMed)

  1431: Martin et al. (2001) "Association of single-nucleotide polymorphisms of the tau gene with late-onset Parkinson disease." JAMA 286(18):2245-2250 (PubMed)

  2325: Wei et al. (2003) "Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility." Genes Dev. 17(5):603-614 (PubMed)