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Entries tagged Body Height (94)

3134: Donlon et al. (2012) "FOXO3 gene variants and human aging: coding variants may not be key players." J. Gerontol. A Biol. Sci. Med. Sci. 67(11):1132-1139 (PubMed)

1 citation in connected databases
- Tags:
- Humans
- Female
- Male
- Longevity/genetics
- Aging/genetics
- Alleles
- Chromosome Mapping
- Middle Aged
- Cohort Studies
- Aged
- Aged, 80 and over
- Case-Control Studies
- Genetic Variation
- European Continental Ancestry Group/genetics
- Polymorphism, Single Nucleotide
- Sensitivity and Specificity
- Forkhead Transcription Factors/genetics
- Asian Americans/genetics
- Open Reading Frames/genetics
3159: Concetti et al. (2013) "The functional VNTR MNS16A of the TERT gene is associated with human longevity in a population of Central Italy." Exp. Gerontol. 48(6):587-592 (PubMed)

1 citation in connected databases
- Tags:
- Humans
- Female
- Male
- Longevity/genetics
- Telomerase/genetics
- Adult
- Genetic Predisposition to Disease
- Adolescent
- Middle Aged
- Risk Factors
- Aged
- Aged, 80 and over
- European Continental Ancestry Group/genetics
- Polymorphism, Single Nucleotide
- Italy
- Young Adult
- Minisatellite Repeats/genetics
3221: Jian-Gang et al. (1998) "Apolipoprotein E and longevity among Han Chinese population." Mech. Ageing Dev. 104(2):159-167 (PubMed)

1 citation in connected databases
- Tags:
- Humans
- Female
- Genotype
- Male
- Longevity/genetics
- Alleles
- Adult
- Middle Aged
- Aged
- Aged, 80 and over
- Gene Frequency
- Apolipoproteins E/genetics
- Asian Continental Ancestry Group/genetics
- Sex Distribution
- Age Distribution
2425: Ayyadevara et al. (2009) "Caenorhabditis elegans PI3K mutants reveal novel genes underlying exceptional stress resistance and lifespan." Aging Cell 8(6):706-725 (PubMed)

6 citations in connected databases
- Tags:
- Animals
- Longevity
- Mutation
- Alleles
- Transcription, Genetic
- Binding Sites
- Gene Expression Regulation
- Oligonucleotide Array Sequence Analysis
- RNA Interference
- Caenorhabditis elegans Proteins/genetics/metabolism
- Stress, Physiological
- Phosphatidylinositol 3-Kinases/genetics/metabolism
- Caenorhabditis elegans/enzymology/genetics
2550: Belenky et al. (2007) "Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+." Cell 129(3):473-484 (PubMed)

3 citations in connected databases
- Tags:
- Signal Transduction
- NAD/metabolism
- Histone Deacetylases/metabolism
- Sirtuin 2
- Sirtuins/metabolism
- Phosphotransferases (Alcohol Group Acceptor)/metabolism
- N-Glycosyl Hydrolases/metabolism
- Saccharomyces cerevisiae Proteins/metabolism
- Saccharomyces cerevisiae/cytology/genetics/metabolism
- Gene Silencing/drug effects
- Silent Information Regulator Proteins, Saccharomyces cerevisiae/metabolism
- Niacin/metabolism
- Nicotinamidase/metabolism
- Metabolic Networks and Pathways
- Niacinamide/analogs & derivatives/metabolism/pharmacology
- Purine-Nucleoside Phosphorylase/metabolism
2558: Tsuchiya et al. (2006) "Sirtuin-independent effects of nicotinamide on lifespan extension from calorie restriction in yeast." Aging Cell 5(6):505-514 (PubMed)

2 citations in connected databases
- Tags:
- Caloric Restriction
- Sirtuin 2
- Histone Deacetylases/genetics/metabolism
- Sirtuins/metabolism
- Aging/drug effects/physiology
- Longevity/drug effects/physiology
- Cell Division/drug effects/physiology
- Saccharomyces cerevisiae Proteins/genetics/metabolism
- Cell Aging/drug effects/physiology
- Food Deprivation/physiology
- Acetylation/drug effects
- Silent Information Regulator Proteins, Saccharomyces cerevisiae/metabolism
- Niacinamide/metabolism/pharmacology
- Saccharomyces cerevisiae/drug effects/metabolism
2688: Quinn et al. (2010) "Serum and muscle interleukin-15 levels decrease in aging mice: correlation with declines in soluble interleukin-15 receptor alpha expression." Exp. Gerontol. 45(2):106-112 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Mice
- Body Weight/physiology
- Male
- Mice, Inbred C57BL
- Mice, Inbred C3H
- RNA, Messenger/metabolism
- Aging/metabolism
- Signal Transduction/physiology
- Models, Animal
- Gene Expression/physiology
- Neoplasms/metabolism
- Body Composition
- Interleukin-15/blood/genetics
- Interleukin-15 Receptor alpha Subunit/blood/genetics
- Quadriceps Muscle/metabolism
- Sarcopenia/metabolism
2851: Toroser et al. (2006) "Mechanisms of gamma-glutamylcysteine ligase regulation." Biochim. Biophys. Acta 1760(2):233-244 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Mice
- Male
- Mice, Inbred C57BL
- Phosphorylation
- Signal Transduction
- Rats
- Kinetics
- Enzyme Activation
- Brain/enzymology
- Myocardium/enzymology
- Liver/enzymology
- Rats, Inbred F344
- NADP/metabolism
- Drosophila melanogaster
- Hydrogen-Ion Concentration
- Adenosine Triphosphate/pharmacology
- Protein Kinase Inhibitors/pharmacology
- Buthionine Sulfoximine/pharmacology
- Chromatography, High Pressure Liquid
- Allosteric Regulation
- Glutamate-Cysteine Ligase/antagonists & inhibitors/metabolism
1459: Argyropoulos et al. (1998) "Effects of mutations in the human uncoupling protein 3 gene on the respiratory quotient and fat oxidation in severe obesity and type 2 diabetes." J. Clin. Invest. 102(7):1345-1351 (PubMed)

1 citation in connected databases
- Tags:
- Humans
- Female
- Male
- Polymerase Chain Reaction
- Point Mutation
- Base Sequence
- Protein Conformation
- Codon, Terminator
- Pedigree
- Models, Molecular
- Exons
- Heterozygote Detection
- Polymorphism, Genetic
- European Continental Ancestry Group/genetics
- Energy Metabolism/genetics
- Alternative Splicing
- African Continental Ancestry Group/genetics
- Lipolysis/genetics
- Mitochondrial Proteins
- Ion Channels
- Carrier Proteins/chemistry/genetics
- Diabetes Mellitus/genetics/metabolism
- Diabetes Mellitus, Type 2/genetics/metabolism
- Ethnic Groups
- Obesity
- Oxygen Consumption/genetics
- Sierra Leone
1996: Rung et al. (2009) "Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia." Nat. Genet. 41(10):1110-1115 (PubMed)

1 citation in connected databases
- Tags:
- Humans
- Female
- Male
- Alleles
- Adult
- Phosphatidylinositol 3-Kinases/metabolism
- Middle Aged
- Genome, Human
- European Continental Ancestry Group/genetics
- Polymorphism, Single Nucleotide
- Insulin Resistance
- Muscle, Skeletal/metabolism/pathology
- Biopsy
- Diabetes Mellitus, Type 2/complications/genetics/metabolism/pathology
- Genome-Wide Association Study
- Hyperinsulinism/complications/genetics/metabolism/pathology
- Insulin Receptor Substrate Proteins/genetics
1313: Eggenschwiler et al. (1997) "Mouse mutant embryos overexpressing IGF-II exhibit phenotypic features of the Beckwith-Wiedemann and Simpson-Golabi-Behmel syndromes." Genes Dev. 11(23):3128-3142 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Disease Models, Animal
- Humans
- Mice
- Female
- Male
- Mice, Mutant Strains
- Phenotype
- Crosses, Genetic
- Nuclear Proteins/genetics
- Sequence Deletion
- Gene Expression Regulation, Developmental
- Fetal Death
- Heart Defects, Congenital
- Fetus/abnormalities
- Bone and Bones/abnormalities/embryology
- Abnormalities, Multiple/etiology/genetics/metabolism
- Adrenal Cortex/abnormalities/embryology
- Beckwith-Wiedemann Syndrome/etiology/genetics/metabolism
- Cleft Palate/embryology
- Cyclin-Dependent Kinase Inhibitor p57
- Eye Abnormalities/embryology
- Hernia, Umbilical/embryology
- Insulin-Like Growth Factor II/biosynthesis/genetics/physiology
- Receptor, IGF Type 2/genetics/metabolism
2499: Anderson et al. (2003) "Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae." Nature 423(6936):181-185 (PubMed)

3 citations in connected databases
- Tags:
- Gene Expression Regulation, Fungal
- Longevity/genetics/physiology
- Cell Nucleus/metabolism
- NAD/metabolism
- Histone Deacetylases/metabolism
- Caloric Restriction
- Sirtuin 2
- Gene Silencing
- Sirtuins/metabolism
- Cytoplasm/metabolism
- Heat-Shock Response
- Energy Metabolism
- Saccharomyces cerevisiae Proteins/genetics/metabolism
- Saccharomyces cerevisiae/cytology/enzymology/genetics/metabolism
- Niacinamide/metabolism
- Silent Information Regulator Proteins, Saccharomyces cerevisiae/metabolism
- Niacin/metabolism
- Nicotinamidase/genetics/metabolism
2508: Eisenberg et al. (2009) "Induction of autophagy by spermidine promotes longevity." Nat. Cell Biol. 11(11):1305-1314 (PubMed)

14 citations in connected databases
- Tags:
- Animals
- Humans
- Mice
- Female
- Male
- Mice, Inbred C57BL
- Adult
- HeLa Cells
- Acetylation
- Histones/metabolism
- Longevity/drug effects
- Hydrogen-Ion Concentration
- Necrosis
- Autophagy/drug effects
- Caenorhabditis elegans/drug effects/immunology/physiology
- Drosophila melanogaster/drug effects/immunology/physiology
- Saccharomyces cerevisiae/drug effects/immunology/physiology
- Spermidine/pharmacology
2527: Liu et al. (2010) "The polarisome is required for segregation and retrograde transport of protein aggregates." Cell 140(2):257-267 (PubMed)

3 citations in connected databases
- Tags:
- Heat-Shock Proteins/metabolism
- Mitosis
- Protein Transport
- Saccharomyces cerevisiae Proteins/metabolism
- Actins/metabolism
- Silent Information Regulator Proteins, Saccharomyces cerevisiae/metabolism
- Chaperonins/metabolism
- Microfilament Proteins/metabolism
- Organelles/metabolism
- Saccharomyces cerevisiae/cytology/metabolism
- Sirtuin 2/metabolism
3194: Feng et al. (2011) "Association of mtDNA haplogroup F with healthy longevity in the female Chuang population, China." Exp. Gerontol. 46(12):987-993 (PubMed)

1 citation in connected databases
- Tags:
- Humans
- Female
- Genotype
- Aging/genetics/physiology
- Phenotype
- Longevity/genetics/physiology
- Middle Aged
- Aged
- Aged, 80 and over
- Gene Frequency
- DNA, Mitochondrial/genetics
- Asian Continental Ancestry Group/genetics
- Haplotypes/genetics
- Phylogeny
- China/epidemiology
3367: Lombard et al. (2007) "Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation." Mol. Cell. Biol. 27(24):8807-8814 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Gene Targeting
- Mice
- Sequence Homology, Amino Acid
- Acetylation
- Histone Deacetylases/metabolism
- Feeding Behavior
- Sirtuin 2
- Lysine/metabolism
- Solubility
- Food Deprivation
- Thermogenesis
- Sirtuins/deficiency/metabolism
- Mitochondria, Liver/enzymology/metabolism
- Sirtuin 3
- Silent Information Regulator Proteins, Saccharomyces cerevisiae/metabolism
- Mitochondrial Proteins/deficiency/metabolism
- Adipose Tissue, Brown/cytology
- Glutamate Dehydrogenase/metabolism
- Mammals/metabolism
3383: Bailey-Downs et al. (2012) "Liver-specific knockdown of IGF-1 decreases vascular oxidative stress resistance by impairing the Nrf2-dependent antioxidant response: a novel model of vascular aging." J. Gerontol. A Biol. Sci. Med. Sci. 67(4):313-329 (PubMed)

2 citations in connected databases
- Tags:
- Animals
- Disease Models, Animal
- Mice
- Female
- Male
- Mice, Inbred C57BL
- Apoptosis
- Oxidative Stress
- Hydrogen Peroxide/metabolism
- Aging/metabolism
- Liver/metabolism
- Lipoproteins, LDL/metabolism
- Tissue Culture Techniques
- Hyperglycemia/metabolism
- Gene Knockdown Techniques
- Aorta/metabolism
- Glutamate-Cysteine Ligase/biosynthesis
- Heme Oxygenase-1/biosynthesis
- Insulin-Like Growth Factor I/analysis/biosynthesis/genetics
- Membrane Proteins/biosynthesis
- NAD(P)H Dehydrogenase (Quinone)/biosynthesis
- NF-E2-Related Factor 2/biosynthesis
3970: Yang et al. (2009) "The effect of different ubiquinones on lifespan in Caenorhabditis elegans." Mech. Ageing Dev. 130(6):370-376 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Longevity/genetics
- Oxidative Stress
- Mutation
- Reactive Oxygen Species/metabolism
- Hydrogen Peroxide/metabolism
- Time Factors
- Mitochondria/metabolism
- Caenorhabditis elegans Proteins/genetics/metabolism
- Cell Respiration
- Mitochondrial Proteins/metabolism
- Caenorhabditis elegans/enzymology/genetics
- Ubiquinone/genetics/metabolism
4127: Schlernitzauer et al. (2013) "Chicoric acid is an antioxidant molecule that stimulates AMP kinase pathway in L6 myotubes and extends lifespan in Caenorhabditis elegans." PLoS ONE 8(11):e78788 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Antioxidants/pharmacology
- Longevity/drug effects/physiology
- Transcription Factors/biosynthesis/genetics
- Caenorhabditis elegans/enzymology/genetics
- Muscle Fibers, Skeletal/enzymology
- Caenorhabditis elegans Proteins/biosynthesis/genetics
- Caffeic Acids/pharmacology
- Adenylate Kinase/genetics/metabolism
- Citrate (si)-Synthase/biosynthesis/genetics
- Gene Expression Regulation, Enzymologic/drug effects/genetics
- Oxidoreductases/biosynthesis/genetics
- Succinates/pharmacology
2591: Weinberger et al. (2010) "Growth signaling promotes chronological aging in budding yeast by inducing superoxide anions that inhibit quiescence." Aging (Albany NY) 2(10):709-726 (PubMed)

2 citations in connected databases
- Tags:
- Gene Deletion
- Antioxidants/pharmacology
- Models, Biological
- Catalase/genetics
- Superoxide Dismutase/genetics
- Hydrogen Peroxide/metabolism
- Signal Transduction/physiology
- Apoptosis/drug effects/physiology
- Caloric Restriction
- Hydrogen-Ion Concentration
- Longevity/drug effects/physiology
- Cell Aging/drug effects/physiology
- Protein Kinases/genetics
- Saccharomyces cerevisiae Proteins/genetics
- S Phase/physiology
- Protein-Serine-Threonine Kinases/genetics
- Superoxides/metabolism
- Cell Proliferation/drug effects
- DNA Damage/drug effects/physiology
- Glucose/pharmacology
- Culture Media/metabolism/pharmacology
- Cyclin-Dependent Kinase Inhibitor Proteins/genetics
- G0 Phase/drug effects/physiology
- G1 Phase/drug effects/physiology
- Saccharomyces cerevisiae/drug effects/physiology