Entries tagged Mitochondria, Heart/drug effects/enzymology (107)

  4553: Abergel et al. (2017) "Synergism between soluble guanylate cyclase signaling and neuropeptides extends lifespan in the nematode Caenorhabditis elegans." Aging Cell 16(2):401-413 (PubMed)

  4634: Akhoon et al. (2016) "Withanolide A offers neuroprotection, ameliorates stress resistance and prolongs the life expectancy of Caenorhabditis elegans." Exp. Gerontol. 78:47-56 (PubMed)

  3136: Kim et al. (2012) "Telomere maintenance genes SIRT1 and XRCC6 impact age-related decline in telomere length but only SIRT1 is associated with human longevity." Biogerontology 13(2):119-131 (PubMed)

  3277: Schmeisser et al. (2013) "Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide." Nat. Chem. Biol. 9(11):693-700 (PubMed)

  3497: Chen et al. (2009) "The conserved NAD(H)-dependent corepressor CTBP-1 regulates Caenorhabditis elegans life span." Proc. Natl. Acad. Sci. U.S.A. 106(5):1496-1501 (PubMed)

  3553: Chondrogianni et al. (2015) "20S proteasome activation promotes life span extension and resistance to proteotoxicity in Caenorhabditis elegans." FASEB J. 29(2):611-622 (PubMed)

  3921: Kampkötter et al. (2008) "Increase of stress resistance and lifespan of Caenorhabditis elegans by quercetin." Comp. Biochem. Physiol. B, Biochem. Mol. Biol. 149(2):314-323 (PubMed)

  3949: Morcos et al. (2008) "Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans." Aging Cell 7(2):260-269 (PubMed)

  4014: Ching et al. (2011) "Celecoxib extends C. elegans lifespan via inhibition of insulin-like signaling but not cyclooxygenase-2 activity." Aging Cell 10(3):506-519 (PubMed)

  4033: Schmeisser et al. (2011) "Lonidamine extends lifespan of adult Caenorhabditis elegans by increasing the formation of mitochondrial reactive oxygen species." Horm. Metab. Res. 43(10):687-692 (PubMed)

  1073: Cohen et al. (2004) "Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis." Mol. Cell 13(5):627-638 (PubMed)

  1496: Fridell et al. (2005) "Targeted expression of the human uncoupling protein 2 (hUCP2) to adult neurons extends life span in the fly." Cell Metab. 1(2):145-152 (PubMed)

  2045: Telgmann et al. (2009) "Molecular genetic analysis of a human insulin-like growth factor 1 promoter P1 variation." FASEB J. 23(5):1303-1313 (PubMed)

  2390: Martínez-Azorín et al. (2008) "Over-expression of the catalytic core of mitochondrial DNA (mtDNA) polymerase in the nervous system of Drosophila melanogaster reduces median life span by inducing mtDNA depletion." J. Neurochem. 105(1):165-176 (PubMed)

  983: Li et al. (2004) "Identification and biochemical characterization of a Werner's syndrome protein complex with Ku70/80 and poly(ADP-ribose) polymerase-1." J. Biol. Chem. 279(14):13659-13667 (PubMed)

  984: Loetscher et al. (1987) "Poly(ADP-ribose) may signal changing metabolic conditions to the chromatin of mammalian cells." Proc. Natl. Acad. Sci. U.S.A. 84(5):1286-1289 (PubMed)

  227: Takakura et al. (2001) "Telomerase activation by histone deacetylase inhibitor in normal cells." Nucleic Acids Res. 29(14):3006-3011 (PubMed)

  4216: Rathor et al. (2015) "Folic acid supplementation at lower doses increases oxidative stress resistance and longevity in Caenorhabditis elegans." Age (Dordr) 37(6):113 (PubMed)

  4418: Seah et al. (2016) "Autophagy-mediated longevity is modulated by lipoprotein biogenesis." Autophagy 12(2):261-272 (PubMed)

  4628: Mishur et al. (2016) "Mitochondrial metabolites extend lifespan." Aging Cell 15(2):336-348 (PubMed)