Entries tagged DNA/analysis (72)

  3415: Dutchak et al. (2012) "Fibroblast growth factor-21 regulates PPARγ activity and the antidiabetic actions of thiazolidinediones." Cell 148(3):556-567 (PubMed)

  3505: Folick et al. (2015) "Aging. Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans." Science 347(6217):83-86 (PubMed)

  3579: Wang et al. (2008) "Fat metabolism links germline stem cells and longevity in C. elegans." Science 322(5903):957-960 (PubMed)

  1124: Flodby et al. (1996) "Increased hepatic cell proliferation and lung abnormalities in mice deficient in CCAAT/enhancer binding protein alpha." J. Biol. Chem. 271(40):24753-24760 (PubMed)

  1128: Wang et al. (1995) "Impaired energy homeostasis in C/EBP alpha knockout mice." Science 269(5227):1108-1112 (PubMed)

  1788: Engel et al. (2006) "Full reversal of Alzheimer's disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3." J. Neurosci. 26(19):5083-5090 (PubMed)

  2161: Yap et al. (2009) "Upregulation of Eps8 in oral squamous cell carcinoma promotes cell migration and invasion through integrin-dependent Rac1 activation." Oncogene 28(27):2524-2534 (PubMed)

  2373: Mukhopadhyay et al. (2005) "C. elegans tubby regulates life span and fat storage by two independent mechanisms." Cell Metab. 2(1):35-42 (PubMed)

  2480: Phillips et al. (1989) "Null mutation of copper/zinc superoxide dismutase in Drosophila confers hypersensitivity to paraquat and reduced longevity." Proc. Natl. Acad. Sci. U.S.A. 86(8):2761-2765 (PubMed)

  765: Hirosumi et al. (2002) "A central role for JNK in obesity and insulin resistance." Nature 420(6913):333-336 (PubMed)

  479: Watanabe et al. (1994) "Differential expressions of the topoisomerase II alpha and II beta mRNAs in developing rat brain." Neurosci. Res. 19(1):51-57 (PubMed)

  4616: Qi et al. (2017) "The ω-3 fatty acid α-linolenic acid extends Caenorhabditis elegans lifespan via NHR-49/PPARα and oxidation to oxylipins." Aging Cell 16(5):1125-1135 (PubMed)

  1505: Zhang et al. (2001) "Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes." Cell 105(6):745-755 (PubMed)

  2382: Broughton et al. (2008) "Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs." PLoS ONE 3(11):e3721 (PubMed)

  1717: McLean et al. (2004) "Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression." Genes Dev. 18(24):2998-3003 (PubMed)

  1869: Olswang et al. (2002) "A mutation in the peroxisome proliferator-activated receptor gamma-binding site in the gene for the cytosolic form of phosphoenolpyruvate carboxykinase reduces adipose tissue size and fat content in mice." Proc. Natl. Acad. Sci. U.S.A. 99(2):625-630 (PubMed)

  1890: Marmorstein et al. (2002) "Aberrant accumulation of EFEMP1 underlies drusen formation in Malattia Leventinese and age-related macular degeneration." Proc. Natl. Acad. Sci. U.S.A. 99(20):13067-13072 (PubMed)

  4431: Xu et al. (2003) "The Drosophila microRNA Mir-14 suppresses cell death and is required for normal fat metabolism." Curr. Biol. 13(9):790-795 (PubMed)

  3334: Robert et al. (2008) "Rapid increase in human life expectancy: will it soon be limited by the aging of elastin?" Biogerontology 9(2):119-133 (PubMed)

  3508: Schiavi et al. (2013) "Autophagy induction extends lifespan and reduces lipid content in response to frataxin silencing in C. elegans." Exp. Gerontol. 48(2):191-201 (PubMed)