Entries tagged Cyclin-Dependent Kinases/drug effects/metabolism (26)

  1688: Zhang et al. (2003) "The role of the Grb2-p38 MAPK signaling pathway in cardiac hypertrophy and fibrosis." J. Clin. Invest. 111(6):833-841 (PubMed)

  1718: Ilić et al. (1995) "Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice." Nature 377(6549):539-544 (PubMed)

  1879: Conover et al. (2004) "Metalloproteinase pregnancy-associated plasma protein A is a critical growth regulatory factor during fetal development." Development 131(5):1187-1194 (PubMed)

  485: Sha et al. (1995) "Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses." Cell 80(2):321-330 (PubMed)

  2593: Burtner et al. (2011) "A genomic analysis of chronological longevity factors in budding yeast." Cell Cycle 10(9):1385-1396 (PubMed)

  1717: McLean et al. (2004) "Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression." Genes Dev. 18(24):2998-3003 (PubMed)

  4637: Ding et al. (2017) "Benzimidazole derivative M084 extends the lifespan of Caenorhabditis elegans in a DAF-16/FOXO-dependent way." Mol. Cell. Biochem. 426(1-2):101-109 (PubMed)

  127: Herrera et al. (1996) "TGF beta-induced growth inhibition in primary fibroblasts requires the retinoblastoma protein." Mol. Biol. Cell 7(9):1335-1342 (PubMed)

  743: Loos et al. (1976) "Familial deficiency of glutathione reductase in human blood cells." Blood 48(1):53-62 (PubMed)

  998: Torsoni et al. (2003) "Focal adhesion kinase is activated and mediates the early hypertrophic response to stretch in cardiac myocytes." Circ. Res. 93(2):140-147 (PubMed)

  1296: Wolpowitz et al. (2000) "Cysteine-rich domain isoforms of the neuregulin-1 gene are required for maintenance of peripheral synapses." Neuron 25(1):79-91 (PubMed)

  3778: Cho et al. (2004) "Morphological adjustment of senescent cells by modulating caveolin-1 status." J. Biol. Chem. 279(40):42270-42278 (PubMed)

  1593: Bianchi et al. (2006) "p53 and p66 proteins compete for hypoxia-inducible factor 1 alpha stabilization in young and old rat hearts exposed to intermittent hypoxia." Gerontology 52(1):17-23 (PubMed)

  3526: Cutler et al. (2014) "Sphingolipid metabolism regulates development and lifespan in Caenorhabditis elegans." Mech. Ageing Dev. 143-144:9-18 (PubMed)

  2183: Marshall et al. (2010) "Deficiency of the dual ubiquitin/SUMO ligase Topors results in genetic instability and an increased rate of malignancy in mice." BMC Mol. Biol. 11:31 (PubMed)

  2316: Childress et al. (1996) "LAG2, a gene that determines yeast longevity." Microbiology (Reading, Engl.) 142 ( Pt 8):2289-2297 (PubMed)

  2317: Easlon et al. (2007) "The dihydrolipoamide acetyltransferase is a novel metabolic longevity factor and is required for calorie restriction-mediated life span extension." J. Biol. Chem. 282(9):6161-6171 (PubMed)

  4080: Soh et al. (2013) "Curcumin is an early-acting stage-specific inducer of extended functional longevity in Drosophila." Exp. Gerontol. 48(2):229-239 (PubMed)

  1594: Baker et al. (2006) "Early aging-associated phenotypes in Bub3/Rae1 haploinsufficient mice." J. Cell Biol. 172(4):529-540 (PubMed)

  2314: Feng et al. (2001) "Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans." Dev. Cell 1(5):633-644 (PubMed)