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Entries tagged Chloramphenicol O-Acetyltransferase/metabolism (88)

4582: Nakatani et al. (2018) "Sesamin extends lifespan through pathways related to dietary restriction in Caenorhabditis elegans." Eur J Nutr 57(3):1137-1146 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Mutation
- Survival Analysis
- Gene Expression Regulation, Developmental
- Gene Expression Profiling
- Oligonucleotide Array Sequence Analysis
- RNA Interference
- Dietary Supplements
- Sirtuins/antagonists & inhibitors/genetics/metabolism
- Gene Knockdown Techniques
- Caloric Restriction/adverse effects
- Caenorhabditis elegans Proteins/antagonists & inhibitors/genetics/metabolism
- Antioxidants/administration & dosage
- TOR Serine-Threonine Kinases/antagonists & inhibitors/genetics/metabolism
- AMP-Activated Protein Kinases/antagonists & inhibitors/genetics/metabolism
- Caenorhabditis elegans/enzymology/growth & development/metabolism
- Dioxoles/administration & dosage
- Food Additives/chemistry
- Intrinsically Disordered Proteins/antagonists & inhibitors/genetics/metabolism
- Lignans/administration & dosage
- gamma-Cyclodextrins/chemistry
4755: Champigny et al. (2018) "Omega-3 Monoacylglyceride Effects on Longevity, Mitochondrial Metabolism and Oxidative Stress: Insights from " Mar Drugs 16(11): (PubMed)

2 citations in connected databases
- Tags:
- Animals
- Male
- Models, Animal
- Longevity/drug effects
- Drosophila melanogaster
- Lipid Peroxidation/drug effects
- Oxidative Stress/drug effects
- Mitochondria/drug effects/metabolism
- Dietary Supplements
- Monoglycerides/pharmacology
1550: Canudas et al. (2005) "Hyperphosphorylation of microtubule-associated protein tau in senescence-accelerated mouse (SAM)." Mech. Ageing Dev. 126(12):1300-1304 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Mice
- Aging
- Phosphorylation
- Mice, Transgenic
- Cell Aging
- Blotting, Western
- Tissue Distribution
- Cell Membrane/metabolism
- Brain/metabolism/pathology
- Microtubules/metabolism
- Neurons/metabolism
- Protein Isoforms
- tau Proteins/chemistry/metabolism
- Axons/metabolism
- Cyclin-Dependent Kinase 5/metabolism
- Tubulin/metabolism
1648: Rüttiger et al. (2007) "BDNF mRNA expression and protein localization are changed in age-related hearing loss." Neurobiol. Aging 28(4):586-601 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Disease Models, Animal
- Mice
- Mice, Knockout
- Rats
- RNA, Messenger/metabolism
- Age Factors
- Brain-Derived Neurotrophic Factor/genetics/metabolism
- Reverse Transcriptase Polymerase Chain Reaction/methods
- Gene Expression Regulation/physiology
- Rats, Inbred F344
- Neurons/metabolism
- In Situ Hybridization/methods
- Fluorescent Antibody Technique/methods
- Cell Count/methods
- Cochlea/pathology
- Evoked Potentials, Auditory, Brain Stem/physiology
- Gerbillinae
- Presbycusis/genetics/metabolism/pathology/physiopathology
- Receptor, trkB/deficiency
- Spiral Ganglion/pathology
1742: Cohen et al. (2001) "Selective deletion of leptin receptor in neurons leads to obesity." J. Clin. Invest. 108(8):1113-1121 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Gene Targeting
- Mice
- Mice, Knockout
- Female
- Male
- Carrier Proteins/genetics
- Signal Transduction
- Phenotype
- Brain/metabolism
- RNA/genetics/metabolism
- Triglycerides/metabolism
- Receptors, Cell Surface
- Receptors, Leptin
- Liver/metabolism/pathology
- Neurons/metabolism
- Mice, Obese
- Leptin/metabolism
- Obesity/etiology/genetics/metabolism
1922: Li et al. (2008) "SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons." Cell Metab. 8(1):38-48 (PubMed)

4 citations in connected databases
- Tags:
- Animals
- Oxidative Stress
- Signal Transduction
- Rats
- Phosphoproteins/metabolism
- ras Proteins/metabolism
- Sirtuin 1
- Insulin Receptor Substrate Proteins
- Neurons/metabolism
- Intracellular Signaling Peptides and Proteins/metabolism
- Receptor, IGF Type 1/metabolism
- Mitogen-Activated Protein Kinase 3/metabolism
- Cerebral Cortex/cytology
- Sirtuins/antagonists & inhibitors/physiology
1091: Hwangbo et al. (2004) "Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body." Nature 429(6991):562-566 (PubMed)

5 citations in connected databases
- Tags:
- Animals
- Longevity/physiology
- Aging/physiology
- Signal Transduction
- Forkhead Transcription Factors
- Transcription Factors/genetics/metabolism
- RNA, Messenger/genetics/metabolism
- Survival Rate
- Brain/metabolism
- Organ Specificity
- Stress, Physiological/physiopathology
- Insulin/metabolism
- Receptor, Insulin/genetics/metabolism
- Drosophila melanogaster/physiology
- Drosophila Proteins/genetics/metabolism
- PTEN Phosphohydrolase
- Neurons/metabolism
- Phosphoric Monoester Hydrolases/genetics/metabolism
- Fat Body/metabolism
- Genes, Insect/genetics
- Insect Hormones/genetics/metabolism
1236: O'Bryan et al. (1993) "Clusterin levels increase during neuronal development." J. Neurobiol. 24(4):421-432 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Mice
- Cell Aging/physiology
- Embryonic and Fetal Development/physiology
- RNA, Messenger/biosynthesis
- Clusterin
- Cell Death/physiology
- Nerve Tissue Proteins/metabolism
- Brain/embryology/growth & development/metabolism
- Neurons/metabolism
- Immunoenzyme Techniques
- Mice, Inbred CBA
- Molecular Chaperones
- Glycoproteins/genetics/metabolism
1378: De Strooper et al. (1999) "A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain." Nature 398(6727):518-522 (PubMed)

2 citations in connected databases
- Tags:
- Animals
- Mice
- Signal Transduction
- Cells, Cultured
- Brain/metabolism
- Transcription Factors
- DNA-Binding Proteins/metabolism
- Nuclear Proteins/metabolism
- Fibroblasts/metabolism
- Membrane Proteins/metabolism
- Cytoplasm/metabolism
- Protein Processing, Post-Translational
- Amyloid beta-Protein Precursor/metabolism
- Peptide Fragments/metabolism
- Endopeptidases/metabolism
- Sterol Regulatory Element Binding Protein 1
- Neurons/metabolism
- CCAAT-Enhancer-Binding Proteins
- Amyloid Precursor Protein Secretases
- Aspartic Acid Endopeptidases
- Presenilin-1
- Receptors, Notch
- Alzheimer Disease/drug therapy
1446: Tesseur et al. (2000) "Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice." Am. J. Pathol. 156(3):951-964 (PubMed)

2 citations in connected databases
- Tags:
- Animals
- Humans
- Mice
- Aging
- Phosphorylation
- Survival Rate
- RNA, Messenger/metabolism
- In Situ Hybridization
- tau Proteins/metabolism
- Brain/metabolism/pathology
- DNA Primers/chemistry
- Ubiquitins/metabolism
- Neurons/metabolism
- Apolipoprotein E4
- Inclusion Bodies/metabolism/pathology
- Apolipoproteins E/genetics/metabolism
- Mice, Transgenic/metabolism
2114: Lee et al. (2010) "Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations." Cell 141(7):1146-1158 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Humans
- Mice
- Mice, Knockout
- Gene Deletion
- Proteins/metabolism
- Cell Line
- Hydrolysis
- Neurons/metabolism
- Alzheimer Disease/metabolism/pathology
- Blastocyst/metabolism
- Autophagy
- Gene Knockout Techniques
- Glycosylation
- Lysosomes/metabolism
- Presenilin-1/genetics/metabolism
- Vacuolar Proton-Translocating ATPases/metabolism
- Vacuoles/metabolism
2207: Pasquariello et al. (2009) "Characterization of the endocannabinoid system in human neuronal cells and proteomic analysis of anandamide-induced apoptosis." J. Biol. Chem. 284(43):29413-29426 (PubMed)

1 citation in connected databases
- Tags:
- Humans
- Models, Biological
- Dose-Response Relationship, Drug
- Gene Expression Regulation/drug effects
- Apoptosis/drug effects
- Neurons/metabolism
- Cell Line, Tumor
- Piperidines/pharmacology
- Arachidonic Acids/pharmacology
- Cannabinoid Receptor Modulators/pharmacology
- Endocannabinoids
- Nerve Tissue Proteins/biosynthesis
- Polyunsaturated Alkamides/pharmacology
- Pyrazoles/pharmacology
- Receptor, Cannabinoid, CB1/agonists/metabolism
2270: Lehtinen et al. (2006) "A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span." Cell 125(5):987-981001 (PubMed)

2 citations in connected databases
- Tags:
- Animals
- Longevity/physiology
- Phosphorylation
- Cells, Cultured
- Rats
- Evolution, Molecular
- Cell Aging/physiology
- Oxidative Stress/physiology
- Animals, Newborn
- Protein Structure, Tertiary
- Signal Transduction/physiology
- Transcriptional Activation/physiology
- Protein-Serine-Threonine Kinases/genetics/metabolism
- Cell Death/physiology
- Neurons/metabolism
- Caenorhabditis elegans
- Active Transport, Cell Nucleus/physiology
- 14-3-3 Proteins/metabolism
- Caenorhabditis elegans Proteins/genetics/isolation & purification/metabolism
- Conserved Sequence/physiology
- Forkhead Transcription Factors/chemistry/metabolism
- Nerve Tissue Proteins/chemistry/metabolism
4001: Lee et al. (2010) "Curcumin extends life span, improves health span, and modulates the expression of age-associated aging genes in Drosophila melanogaster." Rejuvenation Res 13(5):561-570 (PubMed)

2 citations in connected databases
- Tags:
- Animals
- Survival Analysis
- Reverse Transcriptase Polymerase Chain Reaction
- Gene Expression Profiling
- Oligonucleotide Array Sequence Analysis
- Gene Expression Regulation/drug effects
- Cluster Analysis
- Transcription, Genetic/drug effects
- Reproducibility of Results
- Oxidative Stress/drug effects
- Genes, Insect/genetics
- Longevity/drug effects/genetics
- Dietary Supplements
- Locomotion/drug effects
- Aging/drug effects/genetics
- Health
- Drosophila melanogaster/drug effects/genetics
- Curcumin/administration & dosage/pharmacology
- Protective Agents/administration & dosage/pharmacology
4061: Shen et al. (2013) "Curcumin-supplemented diets increase superoxide dismutase activity and mean lifespan in Drosophila." Age (Dordr) 35(4):1133-1142 (PubMed)

4 citations in connected databases
- Tags:
- Animals
- Female
- Male
- RNA/genetics
- Gene Expression Regulation
- Superoxide Dismutase/biosynthesis/genetics
- Longevity/drug effects/genetics
- Dietary Supplements
- Aging/drug effects/genetics
- Chromatography, High Pressure Liquid
- Drosophila melanogaster/drug effects/enzymology/genetics
- Real-Time Polymerase Chain Reaction
- Lipid Peroxidation/drug effects/genetics
- Curcumin/pharmacology
4111: Niu et al. (2013) "The phytochemical, EGCG, extends lifespan by reducing liver and kidney function damage and improving age-associated inflammation and oxidative stress in healthy rats." Aging Cell 12(6):1041-1049 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Male
- Rats
- Lipids/blood
- RNA, Messenger/genetics/metabolism
- Aging/pathology
- Rats, Wistar
- Longevity/drug effects
- Gene Expression Regulation/drug effects
- NF-kappa B/genetics/metabolism
- Blood Glucose/metabolism
- Body Weight/drug effects
- Forkhead Transcription Factors/metabolism
- Oxidative Stress/drug effects/genetics
- Kidney Function Tests
- Sirtuin 1/metabolism
- Blood Pressure/drug effects
- Heart Rate/drug effects
- Catechin/analogs & derivatives/pharmacology
- Feeding Behavior/drug effects
- Inflammation/genetics/pathology
- Kidney/drug effects/pathology/physiopathology
- Liver/drug effects/pathology/physiopathology
- Liver Function Tests
- Phytochemicals/pharmacology
3026: Zschocke et al. (2006) "Allelic variation in the CNDP1 gene and its lack of association with longevity and coronary heart disease." Mech. Ageing Dev. 127(11):817-820 (PubMed)

1 citation in connected databases
- Tags:
- Humans
- Female
- Male
- Longevity/genetics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Molecular Sequence Data
- Middle Aged
- Aged
- Aged, 80 and over
- Genetic Variation/genetics
- Coronary Disease/genetics
- Dipeptidases/genetics
4397: Seo et al. (2015) "RNA helicase HEL-1 promotes longevity by specifically activating DAF-16/FOXO transcription factor signaling in Caenorhabditis elegans." Proc. Natl. Acad. Sci. U.S.A. 112(31):E4246-E4255 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Insulin-Like Growth Factor I/metabolism
- Longevity
- Signal Transduction
- Up-Regulation
- Protein Binding
- RNA, Messenger/genetics/metabolism
- Reproduction
- Base Sequence
- Molecular Sequence Data
- Genes, Helminth
- Mutation/genetics
- Gene Expression Regulation, Developmental
- Insulin/metabolism
- Gene Expression Profiling
- RNA Interference
- Caenorhabditis elegans Proteins/genetics/metabolism
- Receptor, Insulin/metabolism
- Neurons/metabolism
- Caenorhabditis elegans/enzymology/genetics/physiology
- Intestines/metabolism
- Sequence Analysis, RNA
- Forkhead Transcription Factors/genetics/metabolism
- Gene Knockdown Techniques
- RNA Helicases/genetics/metabolism
3965: Bahadorani and Hilliker (2008) "Cocoa confers life span extension in Drosophila melanogaster." Nutr Res 28(6):377-382 (PubMed)

2 citations in connected databases
- Tags:
- Animals
- Antioxidants/pharmacology
- Feeding Behavior
- Longevity/drug effects
- Drosophila melanogaster
- Flavonoids/pharmacology
- Anoxia/metabolism
- Oxidative Stress/drug effects
- Dietary Supplements
- Chelating Agents/pharmacology
- Plant Extracts/pharmacology
- Cacao
- Iron
- Reactive Oxygen Species/pharmacology
- Seeds
- Superoxide Dismutase/deficiency
2360: Bishop and Guarente (2007) "Two neurons mediate diet-restriction-induced longevity in C. elegans." Nature 447(7144):545-549 (PubMed)

4 citations in connected databases
- Tags:
- Animals
- Longevity/physiology
- DNA-Binding Proteins/genetics/metabolism
- Transcription Factors/genetics/metabolism
- Models, Biological
- Oxygen Consumption
- Caloric Restriction
- Caenorhabditis elegans Proteins/genetics/metabolism
- Diet
- Neurons/metabolism
- Cell Respiration
- Caenorhabditis elegans/anatomy & histology/cytology/physiology
- Head