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Entries tagged Endothelium, Vascular/cytology (335)

575: Abel et al. (2001) "Expression of expanded repeat androgen receptor produces neurologic disease in transgenic mice." Hum. Mol. Genet. 10(2):107-116 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Mice
- Female
- Male
- Mice, Inbred C57BL
- Mice, Transgenic
- Phenotype
- Transcription, Genetic
- Sequence Deletion
- Promoter Regions, Genetic
- Transgenes
- Behavior, Animal
- Cell Nucleus/ultrastructure
- Trinucleotide Repeat Expansion
- Brain Stem/pathology
- Inclusion Bodies/genetics/metabolism
- Lameness, Animal/genetics/physiopathology
- Muscular Disorders, Atrophic/genetics/metabolism/physiopathology
- Nerve Degeneration/genetics
- Neurofilament Proteins/genetics
- Peptides/genetics
- Prions/genetics
- Receptors, Androgen/genetics/metabolism
816: Ackermann and Brack (1996) "A strong ubiquitous promoter-enhancer for development and aging of Drosophila melanogaster." Nucleic Acids Res. 24(12):2452-2453 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Aging/genetics
- Cell Line
- Enhancer Elements, Genetic
- Promoter Regions, Genetic
- Gene Expression Regulation, Developmental
- Transgenes
- Peptide Elongation Factor 1
- Drosophila melanogaster/genetics
- Peptide Elongation Factors/genetics
3744: Acosta et al. (2008) "Chemokine signaling via the CXCR2 receptor reinforces senescence." Cell 133(6):1006-1018 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Humans
- Mice
- Signal Transduction
- DNA Damage
- Tumor Suppressor Protein p53/metabolism
- Cell Line
- Ligands
- Cell Aging
- NF-kappa B/metabolism
- Fibroblasts/cytology/metabolism
- RNA Interference
- Down-Regulation
- CCAAT-Enhancer-Binding Protein-beta/metabolism
- Cell Line, Tumor
- Chemokines/metabolism
- Adenocarcinoma/metabolism
- Lung Neoplasms/metabolism
- Precancerous Conditions/metabolism
- Receptors, Interleukin-8A/metabolism
- Receptors, Interleukin-8B/genetics/metabolism
3109: Nebel et al. (2007) "Role of the toll-like receptor 4 polymorphism Asp299Gly in longevity and myocardial infarction in German men." Mech. Ageing Dev. 128(5-6):409-411 (PubMed)

1 citation in connected databases
- Tags:
- Humans
- Male
- Longevity/genetics
- Adult
- Middle Aged
- Amino Acid Substitution
- Polymorphism, Genetic
- Aged
- Myocardial Infarction/genetics
- Germany
- Toll-Like Receptor 4/genetics
- Aspartic Acid/chemistry/genetics
- Glycine/chemistry/genetics
3110: Li et al. (2009) "Interactive association of heat shock protein 70 genes variants with natural longevity in Xinjiang Hetian Uygur ethnicity." Transl Res 154(5):257-264 (PubMed)

1 citation in connected databases
- Tags:
- Humans
- Female
- Genotype
- Male
- Longevity/genetics
- Phenotype
- DNA Mutational Analysis
- Polymorphism, Genetic
- Aged
- Aged, 80 and over
- Case-Control Studies
- Asian Continental Ancestry Group/genetics
- Ethnic Groups
- China/ethnology
- HSP70 Heat-Shock Proteins/classification/genetics
3116: Khabour et al. (2010) "Associations of polymorphisms in adiponectin and leptin genes with men's longevity." Aging Male 13(3):188-193 (PubMed)

3 citations in connected databases
- Tags:
- Humans
- Female
- Male
- Longevity/genetics
- Adult
- Middle Aged
- Polymorphism, Genetic
- Aged, 80 and over
- Gene Frequency
- Sex Factors
- Polymorphism, Single Nucleotide
- Young Adult
- Adiponectin/genetics
- Genetic Association Studies/statistics & numerical data
- Jordan/epidemiology
- Leptin/genetics
3120: Laplana et al. (2010) "Tagging long-lived individuals through vitamin-D receptor (VDR) haplotypes." Biogerontology 11(4):437-446 (PubMed)

1 citation in connected databases
- Tags:
- Humans
- Female
- Genotype
- Male
- Longevity/genetics
- Alleles
- Adult
- Adolescent
- Polymorphism, Genetic
- Aged, 80 and over
- Genetic Markers
- Haplotypes
- Young Adult
- Receptors, Calcitriol/genetics
3128: Corbo et al. (2011) "Association of CYP19 and ESR1 pleiotropic genes with human longevity." J. Gerontol. A Biol. Sci. Med. Sci. 66(1):51-55 (PubMed)

2 citations in connected databases
- Tags:
- Humans
- Female
- Genotype
- Male
- Longevity/genetics
- Fertility
- Polymorphism, Genetic
- Aged
- Aged, 80 and over
- Logistic Models
- Aromatase/genetics
- Estrogen Receptor alpha/genetics
- Genetic Pleiotropy
3129: Flachsbart et al. (2011) "Genetic variation in the CYP2C monooxygenase enzyme subfamily shows no association with longevity in a German population." J. Gerontol. A Biol. Sci. Med. Sci. 66(11):1186-1191 (PubMed)

1 citation in connected databases
- Tags:
- Humans
- Female
- Male
- Longevity/genetics
- Linkage Disequilibrium
- Aged, 80 and over
- Genetic Predisposition to Disease/genetics
- Polymorphism, Single Nucleotide
- Genetic Variation/genetics
- Germany
- Aryl Hydrocarbon Hydroxylases/genetics
- Cytochrome P-450 Enzyme System/genetics
- Genetic Association Studies
3133: Morris et al. (2014) "Association analyses of insulin signaling pathway gene polymorphisms with healthy aging and longevity in Americans of Japanese ancestry." J. Gerontol. A Biol. Sci. Med. Sci. 69(3):270-273 (PubMed)

1 citation in connected databases
- Tags:
- Humans
- Genotype
- Male
- Longevity/genetics
- Aging/genetics
- Signal Transduction/genetics
- Cohort Studies
- Aged, 80 and over
- Gene Frequency
- Case-Control Studies
- Polymorphism, Single Nucleotide/genetics
- Insulin-Like Growth Factor I/genetics
- Insulin/genetics
- Genetic Variation/genetics
- Exodeoxyribonucleases/genetics
- Insulin Resistance/genetics
- Polymorphism, Genetic/genetics
- Longitudinal Studies
- Genes, p16/physiology
- DNA Repair Enzymes/genetics
- Forkhead Transcription Factors/genetics
- Asian Americans/genetics
- Japan/ethnology
- Activating Transcription Factor 4/genetics
- Genes, jun/genetics
- Proto-Oncogene Proteins c-cbl/genetics
3136: Kim et al. (2012) "Telomere maintenance genes SIRT1 and XRCC6 impact age-related decline in telomere length but only SIRT1 is associated with human longevity." Biogerontology 13(2):119-131 (PubMed)

2 citations in connected databases
- Tags:
- Humans
- Female
- Genotype
- Male
- Longevity/genetics
- DNA-Binding Proteins/genetics/metabolism
- Phenotype
- Adult
- Telomere/metabolism
- Proportional Hazards Models
- Survival Analysis
- Age Factors
- Middle Aged
- Aged
- Aged, 80 and over
- Gene Frequency
- Case-Control Studies
- Polymorphism, Single Nucleotide
- Odds Ratio
- Multivariate Analysis
- Lod Score
- Antigens, Nuclear/genetics/metabolism
- Sirtuin 1/genetics/metabolism
- Young Adult
- Louisiana
- 3' Flanking Region
- Georgia
- Telomere Shortening
3143: Lindahl-Jacobsen et al. (2013) "Effects of the APOE ε2 allele on mortality and cognitive function in the oldest old." J. Gerontol. A Biol. Sci. Med. Sci. 68(4):389-394 (PubMed)

1 citation in connected databases
- Tags:
- Humans
- Female
- Male
- Alleles
- Genetic Predisposition to Disease
- Risk Factors
- Aged, 80 and over
- Apolipoproteins E/genetics
- Mortality
- Intelligence Tests
- Cognition Disorders/diagnosis/genetics
3161: Zhao et al. (2012) "Common genetic variants of the β2-adrenergic receptor affect its translational efficiency and are associated with human longevity." Aging Cell 11(6):1094-1101 (PubMed)

2 citations in connected databases
- Tags:
- Humans
- Female
- Male
- Longevity/genetics
- Transfection
- Aging/genetics/metabolism
- Linkage Disequilibrium
- Aged, 80 and over
- Genes, Reporter
- Case-Control Studies
- Protein Biosynthesis
- Asian Continental Ancestry Group/genetics
- Polymorphism, Single Nucleotide
- Follow-Up Studies
- Haplotypes
- Questionnaires
- HEK293 Cells
- Mitogen-Activated Protein Kinase 1/genetics/metabolism
- Adenylate Cyclase/genetics/metabolism
- Luciferases, Renilla
- Receptors, Adrenergic, beta-1/genetics/metabolism
- Receptors, Adrenergic, beta-2/genetics/metabolism
3166: Dato et al. (2012) "UCP3 polymorphisms, hand grip performance and survival at old age: association analysis in two Danish middle aged and elderly cohorts." Mech. Ageing Dev. 133(8):530-537 (PubMed)

2 citations in connected databases
- Tags:
- Humans
- Female
- Longevity/physiology
- Male
- Middle Aged
- Cohort Studies
- Aged, 80 and over
- Polymorphism, Single Nucleotide
- Haplotypes
- Hand Strength/physiology
- Denmark
- Endopeptidases/genetics/metabolism
- Ubiquitin-Specific Proteases
3173: Yang et al. (2012) "Mitochondrial DNA polymorphisms are associated with the longevity in the Guangxi Bama population of China." Mol. Biol. Rep. 39(9):9123-9131 (PubMed)

2 citations in connected databases
- Tags:
- Humans
- Female
- Genotype
- Male
- Longevity/genetics
- Aging/genetics
- Adult
- Child
- Adolescent
- Middle Aged
- Polymorphism, Genetic
- Aged
- Aged, 80 and over
- DNA, Mitochondrial/genetics
- Polymorphism, Single Nucleotide
- China
- Young Adult
- Genetic Loci
- Asian Continental Ancestry Group/ethnology
- Gene Order
3208: Ulybina et al. (2010) "Evidence for depletion of CASP5 Ala90Thr heterozygous genotype in aged subjects." Exp. Gerontol. 45(9):726-729 (PubMed)

1 citation in connected databases
- Tags:
- Humans
- Genotype
- Heterozygote
- Homozygote
- Longevity/genetics
- Apoptosis
- Polymerase Chain Reaction
- Adult
- Adolescent
- Middle Aged
- Amino Acid Substitution
- Polymorphism, Genetic
- DNA Primers
- Aged
- Aged, 80 and over
- Gene Frequency
- Lung Neoplasms/genetics
- Smoking/epidemiology
- Caspases/genetics
3259: Nojima et al. (2013) "Haploinsufficiency of akt1 prolongs the lifespan of mice." PLoS ONE 8(7):e69178 (PubMed)

5 citations in connected databases
- Tags:
- Animals
- Humans
- Mice
- Mice, Knockout
- Female
- Longevity/genetics
- Phenotype
- Age Factors
- Caenorhabditis elegans/physiology
- Ribosomes/metabolism
- Mitochondria/genetics/metabolism
- Proto-Oncogene Proteins c-akt/genetics
- Haploinsufficiency/genetics
3272: Caballero et al. (2011) "Absence of mitochondrial translation control proteins extends life span by activating sirtuin-dependent silencing." Mol. Cell 42(3):390-400 (PubMed)

9 citations in connected databases
- Tags:
- Gene Deletion
- Oxidative Stress
- Signal Transduction
- Mutation
- Reactive Oxygen Species/metabolism
- DNA-Binding Proteins
- Transcription Factors
- Gene Expression Regulation, Fungal
- Reverse Transcriptase Polymerase Chain Reaction
- Blotting, Western
- Cell Division/genetics
- Time Factors
- Gene Expression Profiling
- Oligonucleotide Array Sequence Analysis
- Microscopy, Fluorescence
- Cyclic AMP/metabolism
- Saccharomyces cerevisiae Proteins/genetics/metabolism
- Cyclic AMP-Dependent Protein Kinases/metabolism
- Mitochondrial Proteins/genetics/metabolism
- Green Fluorescent Proteins/genetics/metabolism
- Nicotinamidase/genetics/metabolism
- Silent Information Regulator Proteins, Saccharomyces cerevisiae/genetics/metabolism
- Sirtuin 2/genetics/metabolism
3303: Titus et al. (2013) "Impairment of BRCA1-related DNA double-strand break repair leads to ovarian aging in mice and humans." Sci Transl Med 5(172):172ra21 (PubMed)

3 citations in connected databases
- Tags:
- Animals
- Humans
- Mice
- Female
- Mutation
- Mice, Transgenic
- DNA Repair
- Fertility
- Adult
- Child
- Cell Aging
- Age Factors
- Adolescent
- Child, Preschool
- Gene Expression Regulation
- Aging/genetics/metabolism/pathology
- RNA Interference
- BRCA2 Protein/genetics/metabolism
- BRCA1 Protein/genetics/metabolism
- DNA Breaks, Double-Stranded
- Young Adult
- Anti-Mullerian Hormone/blood
- Oocytes/metabolism/pathology
- Ovary/metabolism/pathology/physiopathology
3357: Dawson et al. (2003) "Hyposulfatemia, growth retardation, reduced fertility, and seizures in mice lacking a functional NaSi-1 gene." Proc. Natl. Acad. Sci. U.S.A. 100(23):13704-13709 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Mice
- Mice, Knockout
- Mice, Inbred C57BL
- Body Weight
- Fertility
- Genetic Vectors
- Time Factors
- Exons
- Models, Genetic
- Mutagenesis, Site-Directed
- Blotting, Southern
- RNA/metabolism
- DNA, Complementary/metabolism
- Cytosol/metabolism
- Kidney/metabolism
- Cell Membrane/metabolism
- Liver/metabolism
- Biological Transport
- Intestines/metabolism
- Growth Disorders/etiology
- Symporters/genetics/physiology
- Bile Acids and Salts/blood
- Cation Transport Proteins
- Seizures/etiology
- Sulfates/blood/urine
- Sulfotransferases/metabolism