Entries tagged Zinostatin/pharmacology (101)

  2006: Liu et al. (2011) "Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome." Nature 472(7342):221-225 (PubMed)

  3487: Ohtsuka et al. (2013) "Screening for long-lived genes identifies Oga1, a guanine-quadruplex associated protein that affects the chronological lifespan of the fission yeast Schizosaccharomyces pombe." Mol. Genet. Genomics 288(5-6):285-295 (PubMed)

  3494: Maoz et al. (2015) "The yeast forkhead HCM1 controls life span independent of calorie restriction." J. Gerontol. A Biol. Sci. Med. Sci. 70(4):444-453 (PubMed)

  2264: Rao et al. (2007) "Ceramide transfer protein function is essential for normal oxidative stress response and lifespan." Proc. Natl. Acad. Sci. U.S.A. 104(27):11364-11369 (PubMed)

  2299: Kim et al. (2004) "The histone acetyltransferase GCN5 modulates the retrograde response and genome stability determining yeast longevity." Biogerontology 5(5):305-316 (PubMed)

  2307: Morrow et al. (2004) "Overexpression of the small mitochondrial Hsp22 extends Drosophila life span and increases resistance to oxidative stress." FASEB J. 18(3):598-599 (PubMed)

  2309: Lamming et al. (2005) "HST2 mediates SIR2-independent life-span extension by calorie restriction." Science 309(5742):1861-1864 (PubMed)

  2756: Kong et al. (2012) "Rate of de novo mutations and the importance of father's age to disease risk." Nature 488(7412):471-475 (PubMed)

  3063: Lee et al. (2003) "Polymorphisms in the human homologue of the drosophila Indy (I'm not dead yet) gene." Mech. Ageing Dev. 124(8-9):897-902 (PubMed)

  4030: Schriner et al. (2012) "Extension of Drosophila lifespan by Rosa damascena associated with an increased sensitivity to heat." Biogerontology 13(2):105-117 (PubMed)

  4236: Lentini et al. (2012) "MAD2 depletion triggers premature cellular senescence in human primary fibroblasts by activating a p53 pathway preventing aneuploid cells propagation." J. Cell. Physiol. 227(9):3324-3332 (PubMed)

  4244: Nguyen et al. (2012) "Nek4 regulates entry into replicative senescence and the response to DNA damage in human fibroblasts." Mol. Cell. Biol. 32(19):3963-3977 (PubMed)

  4388: Schwarz et al. (2015) "Siglec receptors impact mammalian lifespan by modulating oxidative stress." Elife 4: (PubMed)

  1514: Yamamoto et al. (2005) "Regulation of oxidative stress by the anti-aging hormone klotho." J. Biol. Chem. 280(45):38029-38034 (PubMed)

  2260: Lin et al. (2000) "Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae." Science 289(5487):2126-2128 (PubMed)

  2304: Rosaleny et al. (2005) "Yeast HAT1 and HAT2 deletions have different life-span and transcriptome phenotypes." FEBS Lett. 579(19):4063-4068 (PubMed)

  2499: Anderson et al. (2003) "Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae." Nature 423(6936):181-185 (PubMed)

  2509: Falcón et al. (2010) "Acetyl-coenzyme A synthetase 2 is a nuclear protein required for replicative longevity in Saccharomyces cerevisiae." Mol. Cell. Biochem. 333(1-2):99-9108 (PubMed)

  3290: Yan et al. (2012) "Common mechanisms for calorie restriction and adenylyl cyclase type 5 knockout models of longevity." Aging Cell 11(6):1110-1120 (PubMed)

  3549: Xu et al. (2014) "Longevity effect of IGF-1R(+/-) mutation depends on genetic background-specific receptor activation." Aging Cell 13(1):19-28 (PubMed)