Entries tagged Exodeoxyribonucleases/metabolism (37)

  1476: Agarwal et al. (2003) "Zinc metalloproteinase, ZMPSTE24, is mutated in mandibuloacral dysplasia." Hum. Mol. Genet. 12(16):1995-2001 (PubMed)

  3253: Rufini et al. (2012) "TAp73 depletion accelerates aging through metabolic dysregulation." Genes Dev. 26(18):2009-2014 (PubMed)

  3490: Mori et al. (2012) "Role of microRNA processing in adipose tissue in stress defense and longevity." Cell Metab. 16(3):336-347 (PubMed)

  1179: Li et al. (2004) "Age-dependent methylation of ESR1 gene in prostate cancer." Biochem. Biophys. Res. Commun. 321(2):455-461 (PubMed)

  1255: Amador-Noguez et al. (2004) "Gene expression profile of long-lived Ames dwarf mice and Little mice." Aging Cell 3(6):423-441 (PubMed)

  1477: Navarro et al. (2005) "Loss of ZMPSTE24 (FACE-1) causes autosomal recessive restrictive dermopathy and accumulation of Lamin A precursors." Hum. Mol. Genet. 14(11):1503-1513 (PubMed)

  1478: Navarro et al. (2004) "Lamin A and ZMPSTE24 (FACE-1) defects cause nuclear disorganization and identify restrictive dermopathy as a lethal neonatal laminopathy." Hum. Mol. Genet. 13(20):2493-2503 (PubMed)

  1774: Denecke et al. (2006) "A homozygous ZMPSTE24 null mutation in combination with a heterozygous mutation in the LMNA gene causes Hutchinson-Gilford progeria syndrome (HGPS): insights into the pathophysiology of HGPS." Hum. Mutat. 27(6):524-531 (PubMed)

  1783: Yang et al. (2005) "Activated IGF-1R inhibits hyperglycemia-induced DNA damage and promotes DNA repair by homologous recombination." Am. J. Physiol. Renal Physiol. 289(5):F1144-F1152 (PubMed)

  1975: Smith et al. (2010) "A role for the Werner syndrome protein in epigenetic inactivation of the pluripotency factor Oct4." Aging Cell 9(4):580-591 (PubMed)

  2579: Tettweiler et al. (2005) "Starvation and oxidative stress resistance in Drosophila are mediated through the eIF4E-binding protein, d4E-BP." Genes Dev. 19(16):1840-1843 (PubMed)

  1098: Sano et al. (2004) "Aprataxin, the causative protein for EAOH is a nuclear protein with a potential role as a DNA repair protein." Ann. Neurol. 55(2):241-249 (PubMed)

  4311: Ma et al. (2016) "NaDC3 Induces Premature Cellular Senescence by Promoting Transport of Krebs Cycle Intermediates, Increasing NADH, and Exacerbating Oxidative Damage." J. Gerontol. A Biol. Sci. Med. Sci. 71(1):1-12 (PubMed)

  4391: Huang et al. (2015) "Tequila Regulates Insulin-Like Signaling and Extends Life Span in Drosophila melanogaster." J. Gerontol. A Biol. Sci. Med. Sci. 70(12):1461-1469 (PubMed)

  3364: Hafner et al. (2010) "Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy." Aging (Albany NY) 2(12):914-923 (PubMed)

  2826: Dillon et al. (1999) "The optical properties of the anterior segment of the eye: implications for cortical cataract." Exp. Eye Res. 68(6):785-795 (PubMed)

  1099: Gueven et al. (2004) "Aprataxin, a novel protein that protects against genotoxic stress." Hum. Mol. Genet. 13(10):1081-1093 (PubMed)

  1895: Michishita et al. (2008) "SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin." Nature 452(7186):492-496 (PubMed)

  2054: Nora et al. (2010) "Telomeric protein TRF2 protects Holliday junctions with telomeric arms from displacement by the Werner syndrome helicase." Nucleic Acids Res. 38(12):3984-3998 (PubMed)

  2410: Ruiz et al. (2011) "Sex-dependent modulation of longevity by two Drosophila homologues of human Apolipoprotein D, GLaz and NLaz." Exp. Gerontol. 46(7):579-589 (PubMed)