Entries tagged Chromosomes/physiology (60)

  3353: Welsch et al. (2010) "Eps8 is recruited to lysosomes and subjected to chaperone-mediated autophagy in cancer cells." Exp. Cell Res. 316(12):1914-1924 (PubMed)

  3366: Qiu et al. (2010) "Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation." Cell Metab. 12(6):662-667 (PubMed)

  3402: Xie et al. (2008) "Overexpression of EIF-5A2 is associated with metastasis of human colorectal carcinoma." Hum. Pathol. 39(1):80-86 (PubMed)

  1043: Treins et al. (2002) "Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway." J. Biol. Chem. 277(31):27975-27981 (PubMed)

  1504: Arsenijevic et al. (2000) "Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production." Nat. Genet. 26(4):435-439 (PubMed)

  1788: Engel et al. (2006) "Full reversal of Alzheimer's disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3." J. Neurosci. 26(19):5083-5090 (PubMed)

  2161: Yap et al. (2009) "Upregulation of Eps8 in oral squamous cell carcinoma promotes cell migration and invasion through integrin-dependent Rac1 activation." Oncogene 28(27):2524-2534 (PubMed)

  2232: Apfeld et al. (2004) "The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans." Genes Dev. 18(24):3004-3009 (PubMed)

  435: Cramer et al. (2003) "HIF-1alpha is essential for myeloid cell-mediated inflammation." Cell 112(5):645-657 (PubMed)

  2862: Stolzing et al. (2008) "Age-related changes in human bone marrow-derived mesenchymal stem cells: consequences for cell therapies." Mech. Ageing Dev. 129(3):163-173 (PubMed)

  1357: Seidler et al. (2004) "Expression level of Wnt signaling components possibly influences the biological behavior of colorectal cancer in different age groups." Exp. Mol. Pathol. 76(3):224-233 (PubMed)

  1365: Rubinfeld et al. (1997) "Stabilization of beta-catenin by genetic defects in melanoma cell lines." Science 275(5307):1790-1792 (PubMed)

  1463: Liu et al. (2005) "Genomic instability in laminopathy-based premature aging." Nat. Med. 11(7):780-785 (PubMed)

  1503: Esterbauer et al. (2001) "A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans." Nat. Genet. 28(2):178-183 (PubMed)

  2160: Chen et al. (2010) "Integrity of SOS1/EPS8/ABI1 tri-complex determines ovarian cancer metastasis." Cancer Res. 70(23):9979-9990 (PubMed)

  4301: Lu et al. (2014) "Suppressing N-Myc downstream regulated gene 1 reactivates senescence signaling and inhibits tumor growth in hepatocellular carcinoma." Carcinogenesis 35(4):915-922 (PubMed)

  3362: Fink et al. (2011) "53BP1 contributes to a robust genomic stability in human fibroblasts." Aging (Albany NY) 3(9):836-845 (PubMed)

  4150: Denzel et al. (2014) "Hexosamine pathway metabolites enhance protein quality control and prolong life." Cell 156(6):1167-1178 (PubMed)

  433: Frenkel-Denkberg et al. (1999) "The function of hypoxia-inducible factor 1 (HIF-1) is impaired in senescent mice." FEBS Lett. 462(3):341-344 (PubMed)

  660: Melov et al. (1998) "A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase." Nat. Genet. 18(2):159-163 (PubMed)