Entries tagged Longevity/drug effects/genetics/physiology/radiation effects (1067)

  3507: Takahashi et al. (2014) "Extended lifespan, reduced body size and leg skeletal muscle mass, and decreased mitochondrial function in clk-1 transgenic mice." Exp. Gerontol. 58:146-153 (PubMed)

  3541: Doze et al. (2011) "Long-term α1A-adrenergic receptor stimulation improves synaptic plasticity, cognitive function, mood, and longevity." Mol. Pharmacol. 80(4):747-758 (PubMed)

  3548: Lopez-Mejia et al. (2014) "Antagonistic functions of LMNA isoforms in energy expenditure and lifespan." EMBO Rep. 15(5):529-539 (PubMed)

  3782: Shvarts et al. (2002) "A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19(ARF)-p53 signaling." Genes Dev. 16(6):681-686 (PubMed)

  3797: Jee et al. (2010) "Nek6 overexpression antagonizes p53-induced senescence in human cancer cells." Cell Cycle 9(23):4703-4710 (PubMed)

  3881: Howitz et al. (2003) "Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan." Nature 425(6954):191-196 (PubMed)

  3889: Matsumoto et al. (2011) "Longevity in mice is promoted by probiotic-induced suppression of colonic senescence dependent on upregulation of gut bacterial polyamine production." PLoS ONE 6(8):e23652 (PubMed)

  3894: Havermann et al. (2014) "Caffeic acid phenethylester increases stress resistance and enhances lifespan in Caenorhabditis elegans by modulation of the insulin-like DAF-16 signalling pathway." PLoS ONE 9(6):e100256 (PubMed)

  3900: Kawano et al. (2005) "Lifespan extending activity of substances secreted by the nematode Caenorhabditis elegans that include the dauer-inducing pheromone." Biosci. Biotechnol. Biochem. 69(12):2479-2481 (PubMed)

  3911: Bonilla et al. (2002) "Extension of life span and stress resistance of Drosophila melanogaster by long-term supplementation with melatonin." Exp. Gerontol. 37(5):629-638 (PubMed)

  3969: Pun et al. (2010) "Ageing in nematodes: do antioxidants extend lifespan in Caenorhabditis elegans?" Biogerontology 11(1):17-30 (PubMed)

  3981: Harrison et al. (2009) "Rapamycin fed late in life extends lifespan in genetically heterogeneous mice." Nature 460(7253):392-395 (PubMed)

  3997: Palermo et al. (2010) "Acetyl-L-carnitine protects yeast cells from apoptosis and aging and inhibits mitochondrial fission." Aging Cell 9(4):570-579 (PubMed)

  4015: Peng et al. (2011) "Apple polyphenols extend the mean lifespan of Drosophila melanogaster." J. Agric. Food Chem. 59(5):2097-2106 (PubMed)

  4019: Powolny et al. (2011) "The garlic constituent diallyl trisulfide increases the lifespan of C. elegans via skn-1 activation." Exp. Gerontol. 46(6):441-452 (PubMed)

  4031: Honda et al. (2011) "Lifespan-extending effects of royal jelly and its related substances on the nematode Caenorhabditis elegans." PLoS ONE 6(8):e23527 (PubMed)

  4035: Yazaki et al. (2011) "Supplemental cellular protection by a carotenoid extends lifespan via Ins/IGF-1 signaling in Caenorhabditis elegans." Oxid Med Cell Longev 2011:596240 (PubMed)

  4039: Saharia et al. (2012) "Reserpine modulates neurotransmitter release to extend lifespan and alleviate age-dependent Aβ proteotoxicity in Caenorhabditis elegans." Exp. Gerontol. 47(2):188-197 (PubMed)

  4053: Zarse et al. (2012) "Impaired insulin/IGF1 signaling extends life span by promoting mitochondrial L-proline catabolism to induce a transient ROS signal." Cell Metab. 15(4):451-465 (PubMed)

  4092: Edwards et al. (2013) "Malate and fumarate extend lifespan in Caenorhabditis elegans." PLoS ONE 8(3):e58345 (PubMed)