Entries tagged Selection, Genetic (830)

  1342: Zhao et al. (2005) "Lifespan extension and elevated hsp gene expression in Drosophila caused by histone deacetylase inhibitors." J. Exp. Biol. 208(Pt 4):697-705 (PubMed)

  1397: Schmitt et al. (2002) "A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy." Cell 109(3):335-346 (PubMed)

  1431: Martin et al. (2001) "Association of single-nucleotide polymorphisms of the tau gene with late-onset Parkinson disease." JAMA 286(18):2245-2250 (PubMed)

  1501: Fleury et al. (1997) "Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia." Nat. Genet. 15(3):269-272 (PubMed)

  1503: Esterbauer et al. (2001) "A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans." Nat. Genet. 28(2):178-183 (PubMed)

  1526: Cheng et al. (2005) "Werner syndrome protein associates with gamma H2AX in a manner that depends upon Nbs1." FEBS Lett. 579(6):1350-1356 (PubMed)

  1528: Cayetanot et al. (2005) "Age effects on pheromone induced Fos expression in olfactory bulbs of a primate." Neuroreport 16(10):1091-1095 (PubMed)

  1529: Riley et al. (2005) "B cells, E2A, and aging." Immunol. Rev. 205:30-47 (PubMed)

  2058: Atzmon et al. (2010) "Evolution in health and medicine Sackler colloquium: Genetic variation in human telomerase is associated with telomere length in Ashkenazi centenarians." Proc. Natl. Acad. Sci. U.S.A. 107 Suppl 1:1710-1717 (PubMed)

  2062: Jaskelioff et al. (2011) "Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice." Nature 469(7328):102-106 (PubMed)

  2070: Wang et al. (2008) "HDAC1 cooperates with C/EBPalpha in the inhibition of liver proliferation in old mice." J. Biol. Chem. 283(38):26169-26178 (PubMed)

  2156: Oh et al. (2010) "Downregulation of lamin A by tumor suppressor AIMP3/p18 leads to a progeroid phenotype in mice." Aging Cell 9(5):810-822 (PubMed)

  2180: Haffner et al. (2007) "Favorable prognostic value of SOCS2 and IGF-I in breast cancer." BMC Cancer 7:136 (PubMed)

  2181: Liu et al. (2008) "Identification of novel epigenetically modified genes in human melanoma via promoter methylation gene profiling." Pigment Cell Melanoma Res 21(5):545-558 (PubMed)

  2189: Iwabuchi et al. (2008) "Characterization of a cancer cell line that expresses a splicing variant form of 53BP1: separation of checkpoint and repair functions in 53BP1." Biochem. Biophys. Res. Commun. 376(3):509-513 (PubMed)

  2191: Bouwman et al. (2010) "53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers." Nat. Struct. Mol. Biol. 17(6):688-695 (PubMed)

  2211: Tanaka et al. (2008) "NF-E2-related factor 2 inhibits lipid accumulation and oxidative stress in mice fed a high-fat diet." J. Pharmacol. Exp. Ther. 325(2):655-664 (PubMed)

  2253: Oh et al. (2006) "Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation." Nat. Genet. 38(2):251-257 (PubMed)

  2297: Thierbach et al. (2005) "Targeted disruption of hepatic frataxin expression causes impaired mitochondrial function, decreased life span and tumor growth in mice." Hum. Mol. Genet. 14(24):3857-3864 (PubMed)

  2313: Schafer et al. (2006) "IFTA-2 is a conserved cilia protein involved in pathways regulating longevity and dauer formation in Caenorhabditis elegans." J. Cell. Sci. 119(Pt 19):4088-4100 (PubMed)