Entries tagged Hematopoietic Stem Cells/enzymology/physiology (25)

  1568: Aguila (1994) "Growth hormone-releasing factor increases somatostatin release and mRNA levels in the rat periventricular nucleus via nitric oxide by activation of guanylate cyclase." Proc. Natl. Acad. Sci. U.S.A. 91(2):782-786 (PubMed)

  1849: Bonawitz et al. (2007) "Reduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expression." Cell Metab. 5(4):265-277 (PubMed)

  2000: Marcheva et al. (2010) "Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes." Nature 466(7306):627-631 (PubMed)

  2120: Nakahata et al. (2008) "The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control." Cell 134(2):329-340 (PubMed)

  2162: Welsch et al. (2007) "Eps8 is increased in pancreatic cancer and required for dynamic actin-based cell protrusions and intercellular cytoskeletal organization." Cancer Lett. 255(2):205-218 (PubMed)

  712: Beg et al. (1995) "Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B." Nature 376(6536):167-170 (PubMed)

  469: Jin et al. (2002) "Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo." Proc. Natl. Acad. Sci. U.S.A. 99(18):11946-11950 (PubMed)

  2535: Piper et al. (2002) "The shortened replicative life span of prohibitin mutants of yeast appears to be due to defective mitochondrial segregation in old mother cells." Aging Cell 1(2):149-157 (PubMed)

  3322: Chung et al. (2008) "HSP72 protects against obesity-induced insulin resistance." Proc. Natl. Acad. Sci. U.S.A. 105(5):1739-1744 (PubMed)

  3713: Alessio et al. (2010) "The BRG1 ATPase of chromatin remodeling complexes is involved in modulation of mesenchymal stem cell senescence through RB-P53 pathways." Oncogene 29(40):5452-5463 (PubMed)

  4035: Yazaki et al. (2011) "Supplemental cellular protection by a carotenoid extends lifespan via Ins/IGF-1 signaling in Caenorhabditis elegans." Oxid Med Cell Longev 2011:596240 (PubMed)

  110: Morrison et al. (1996) "Telomerase activity in hematopoietic cells is associated with self-renewal potential." Immunity 5(3):207-216 (PubMed)

  2544: Greer et al. (2011) "Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans." Nature 479(7373):365-371 (PubMed)

  3340: Itoh et al. (2013) "CCN family member 2/connective tissue growth factor (CCN2/CTGF) has anti-aging effects that protect articular cartilage from age-related degenerative changes." PLoS ONE 8(8):e71156 (PubMed)

  3496: Qian et al. (2015) "PCH-2 regulates Caenorhabditis elegans lifespan." Aging (Albany NY) 7(1):1-13 (PubMed)

  3721: Roy et al. (2010) "DDB2, an essential mediator of premature senescence." Mol. Cell. Biol. 30(11):2681-2692 (PubMed)

  4037: Lublin et al. (2011) "FDA-approved drugs that protect mammalian neurons from glucose toxicity slow aging dependent on cbp and protect against proteotoxicity." PLoS ONE 6(11):e27762 (PubMed)

  1999: Ramsey et al. (2009) "Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis." Science 324(5927):651-654 (PubMed)

  2001: Nakahata et al. (2009) "Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1." Science 324(5927):654-657 (PubMed)

  4416: Tian et al. (2016) "Mitochondrial Stress Induces Chromatin Reorganization to Promote Longevity and UPR(mt)." Cell 165(5):1197-1208 (PubMed)