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Entries tagged Blood Glucose (1340)

3325: Abdouh et al. (2012) "Bmi1 is down-regulated in the aging brain and displays antioxidant and protective activities in neurons." PLoS ONE 7(2):e31870 (PubMed)

2 citations in connected databases
- Tags:
- Animals
- Humans
- Mice
- Mice, Inbred C57BL
- Aging
- Apoptosis
- Oxidative Stress
- Proto-Oncogene Proteins/metabolism
- Reactive Oxygen Species
- Tumor Suppressor Protein p53/metabolism
- Mice, Transgenic
- DNA/metabolism
- Genes, p53
- Antioxidants/metabolism
- Lipid Peroxidation
- Gene Expression Regulation
- Promoter Regions, Genetic
- Nuclear Proteins/metabolism
- Gene Expression Profiling
- Chromatin/metabolism
- Down-Regulation
- Repressor Proteins/metabolism
- Neurons/metabolism
- Polycomb Repressive Complex 1
- Lipids/chemistry
- Brain/metabolism/physiology
- Neurodegenerative Diseases/metabolism/prevention & control
4553: Abergel et al. (2017) "Synergism between soluble guanylate cyclase signaling and neuropeptides extends lifespan in the nematode Caenorhabditis elegans." Aging Cell 16(2):401-413 (PubMed)

3 citations in connected databases
- Tags:
- Animals
- Reactive Oxygen Species/metabolism
- Oxygen/metabolism
- Mutation/genetics
- Temperature
- Gene Expression Regulation/drug effects
- Signal Transduction/drug effects
- Longevity/drug effects/physiology
- Transcription, Genetic/drug effects
- Paraquat/toxicity
- Caenorhabditis elegans Proteins/metabolism
- Neuropeptides/metabolism
- Oxidation-Reduction/drug effects
- Guanylate Cyclase/metabolism
- Food
- Stress, Physiological/drug effects
- Caenorhabditis elegans/drug effects/genetics/physiology
- Neurotransmitter Agents/metabolism
- Immunity, Innate/drug effects/genetics
- Interneurons/drug effects/metabolism
- Receptors, Neuropeptide Y/metabolism
966: Abuzzahab et al. (2003) "IGF-I receptor mutations resulting in intrauterine and postnatal growth retardation." N. Engl. J. Med. 349(23):2211-2222 (PubMed)

1 citation in connected databases
- Tags:
- Growth Disorders/genetics
- Humans
- Insulin-Like Growth Factor I/metabolism
- Female
- Male
- Heterozygote
- Phosphorylation
- Cells, Cultured
- Point Mutation
- Amino Acid Sequence
- Molecular Sequence Data
- Pedigree
- Child, Preschool
- Cohort Studies
- Infant
- Fibroblasts/cytology/metabolism
- Mutation, Missense
- Insulin-Like Growth Factor Binding Protein 3/blood
- Codon, Nonsense
- Fetal Growth Retardation/genetics
- Receptor, IGF Type 1/chemistry/genetics/metabolism
1024: Acampora et al. (1989) "The human HOX gene family." Nucleic Acids Res. 17(24):10385-10402 (PubMed)

2 citations in connected databases
- Tags:
- Humans
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- Molecular Sequence Data
- Sequence Homology, Nucleic Acid
- DNA/genetics
- Exons
- Restriction Mapping
- DNA Probes
- Introns
- Genes, Homeobox
3744: Acosta et al. (2008) "Chemokine signaling via the CXCR2 receptor reinforces senescence." Cell 133(6):1006-1018 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Humans
- Mice
- Signal Transduction
- DNA Damage
- Tumor Suppressor Protein p53/metabolism
- Cell Line
- Ligands
- Cell Aging
- NF-kappa B/metabolism
- Fibroblasts/cytology/metabolism
- RNA Interference
- Down-Regulation
- CCAAT-Enhancer-Binding Protein-beta/metabolism
- Cell Line, Tumor
- Chemokines/metabolism
- Adenocarcinoma/metabolism
- Lung Neoplasms/metabolism
- Precancerous Conditions/metabolism
- Receptors, Interleukin-8A/metabolism
- Receptors, Interleukin-8B/genetics/metabolism
1476: Agarwal et al. (2003) "Zinc metalloproteinase, ZMPSTE24, is mutated in mandibuloacral dysplasia." Hum. Mol. Genet. 12(16):1995-2001 (PubMed)

2 citations in connected databases
- Tags:
- Humans
- Phenotype
- Pedigree
- Lamin Type A/genetics
- Nuclear Proteins/metabolism
- Lipodystrophy/genetics
- Mutation, Missense
- Membrane Proteins/genetics/metabolism
- Sequence Analysis
- Saccharomyces cerevisiae Proteins/genetics
- Atrophy/genetics
- Protein Precursors/metabolism
- Abnormalities, Multiple/etiology/genetics
- Acro-Osteolysis/genetics
- Clavicle/abnormalities
- Lipoproteins/genetics/metabolism
- Mandible/abnormalities
- Metalloendopeptidases/genetics
- Metalloproteases/genetics/metabolism
1568: Aguila (1994) "Growth hormone-releasing factor increases somatostatin release and mRNA levels in the rat periventricular nucleus via nitric oxide by activation of guanylate cyclase." Proc. Natl. Acad. Sci. U.S.A. 91(2):782-786 (PubMed)

2 citations in connected databases
- Tags:
- Animals
- Male
- Rats
- Models, Biological
- RNA, Messenger/genetics/metabolism
- Arginine/analogs & derivatives/pharmacology
- Cycloheximide/pharmacology
- Enzyme Activation/drug effects
- Rats, Sprague-Dawley
- Cyclic GMP/biosynthesis
- Dibutyryl Cyclic GMP/pharmacology
- Gonadotropin-Releasing Hormone/pharmacology
- Guanylate Cyclase/metabolism
- Nitric Oxide/antagonists & inhibitors/metabolism
- Nitroprusside/pharmacology
- Paraventricular Hypothalamic Nucleus/drug effects/metabolism/secretion
- Somatostatin/genetics/secretion
- omega-N-Methylarginine
887: Schreiber-Agus et al. (1998) "Role of Mxi1 in ageing organ systems and the regulation of normal and neoplastic growth." Nature 393(6684):483-487 (PubMed)

3 citations in connected databases
- Tags:
- Animals
- Mice
- Male
- Aging/physiology
- Cell Transformation, Neoplastic
- Phenotype
- Cell Division
- Tumor Suppressor Proteins
- Organ Specificity
- Genes, Tumor Suppressor
- Transcription Factors/physiology
- Neoplasms/etiology
- DNA-Binding Proteins/physiology
- Basic Helix-Loop-Helix Transcription Factors
- Kidney/growth & development/pathology
- Prostate/growth & development/pathology
3442: Ahmed et al. (2010) "Accelerated lipofuscinosis and ubiquitination in granulin knockout mice suggest a role for progranulin in successful aging." Am. J. Pathol. 177(1):311-324 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Humans
- Mice
- Mice, Knockout
- Aging/physiology
- Ubiquitin/metabolism
- Neurons/cytology/metabolism
- Intercellular Signaling Peptides and Proteins/genetics/metabolism
- Ubiquitination
- Brain/cytology/metabolism/pathology
- Neuronal Ceroid-Lipofuscinoses/genetics/metabolism/pathology
451: Akhisaroglu et al. (2003) "Both aging and chronic fluoxetine increase S100B content in the mouse hippocampus." Neuroreport 14(11):1471-1473 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Mice
- Mice, Inbred C57BL
- Aging/physiology
- Blotting, Western
- Nerve Growth Factors/metabolism
- Stimulation, Chemical
- Fluoxetine/pharmacology
- Hippocampus/drug effects/metabolism
- Immunoassay
- Injections, Intraperitoneal
- S100 Proteins/metabolism
- Serotonin Uptake Inhibitors/pharmacology
- S100 Calcium Binding Protein beta Subunit
3091: Bonafè et al. (2001) "A gender--dependent genetic predisposition to produce high levels of IL-6 is detrimental for longevity." Eur. J. Immunol. 31(8):2357-2361 (PubMed)

1 citation in connected databases
- Tags:
- Humans
- Female
- Male
- Homozygote
- Alleles
- DNA Mutational Analysis
- Life Expectancy
- Genetic Predisposition to Disease
- Middle Aged
- Sex Characteristics
- Aged
- Aged, 80 and over
- Gene Frequency
- Promoter Regions, Genetic/genetics
- Longevity/genetics/immunology
- Polymorphism, Genetic/genetics
- Interleukin-6/biosynthesis/blood/genetics
3116: Khabour et al. (2010) "Associations of polymorphisms in adiponectin and leptin genes with men's longevity." Aging Male 13(3):188-193 (PubMed)

3 citations in connected databases
- Tags:
- Humans
- Female
- Male
- Longevity/genetics
- Adult
- Middle Aged
- Polymorphism, Genetic
- Aged, 80 and over
- Gene Frequency
- Sex Factors
- Polymorphism, Single Nucleotide
- Young Adult
- Adiponectin/genetics
- Genetic Association Studies/statistics & numerical data
- Jordan/epidemiology
- Leptin/genetics
3131: Napolioni et al. (2011) "Age- and gender-specific epistasis between ADA and TNF-α influences human life-expectancy." Cytokine 56(2):481-488 (PubMed)

2 citations in connected databases
- Tags:
- Humans
- Female
- Male
- Polymerase Chain Reaction
- Base Sequence
- Adult
- Life Expectancy
- Adolescent
- DNA Primers
- Aged
- Aged, 80 and over
- Epistasis, Genetic
- Tumor Necrosis Factor-alpha/genetics
- Polymorphism, Single Nucleotide
- Young Adult
- Adenosine Deaminase/genetics
3133: Morris et al. (2014) "Association analyses of insulin signaling pathway gene polymorphisms with healthy aging and longevity in Americans of Japanese ancestry." J. Gerontol. A Biol. Sci. Med. Sci. 69(3):270-273 (PubMed)

1 citation in connected databases
- Tags:
- Humans
- Genotype
- Male
- Longevity/genetics
- Aging/genetics
- Signal Transduction/genetics
- Cohort Studies
- Aged, 80 and over
- Gene Frequency
- Case-Control Studies
- Polymorphism, Single Nucleotide/genetics
- Insulin-Like Growth Factor I/genetics
- Insulin/genetics
- Genetic Variation/genetics
- Exodeoxyribonucleases/genetics
- Insulin Resistance/genetics
- Polymorphism, Genetic/genetics
- Longitudinal Studies
- Genes, p16/physiology
- DNA Repair Enzymes/genetics
- Forkhead Transcription Factors/genetics
- Asian Americans/genetics
- Japan/ethnology
- Activating Transcription Factor 4/genetics
- Genes, jun/genetics
- Proto-Oncogene Proteins c-cbl/genetics
3136: Kim et al. (2012) "Telomere maintenance genes SIRT1 and XRCC6 impact age-related decline in telomere length but only SIRT1 is associated with human longevity." Biogerontology 13(2):119-131 (PubMed)

2 citations in connected databases
- Tags:
- Humans
- Female
- Genotype
- Male
- Longevity/genetics
- DNA-Binding Proteins/genetics/metabolism
- Phenotype
- Adult
- Telomere/metabolism
- Proportional Hazards Models
- Survival Analysis
- Age Factors
- Middle Aged
- Aged
- Aged, 80 and over
- Gene Frequency
- Case-Control Studies
- Polymorphism, Single Nucleotide
- Odds Ratio
- Multivariate Analysis
- Lod Score
- Antigens, Nuclear/genetics/metabolism
- Sirtuin 1/genetics/metabolism
- Young Adult
- Louisiana
- 3' Flanking Region
- Georgia
- Telomere Shortening
3161: Zhao et al. (2012) "Common genetic variants of the β2-adrenergic receptor affect its translational efficiency and are associated with human longevity." Aging Cell 11(6):1094-1101 (PubMed)

2 citations in connected databases
- Tags:
- Humans
- Female
- Male
- Longevity/genetics
- Transfection
- Aging/genetics/metabolism
- Linkage Disequilibrium
- Aged, 80 and over
- Genes, Reporter
- Case-Control Studies
- Protein Biosynthesis
- Asian Continental Ancestry Group/genetics
- Polymorphism, Single Nucleotide
- Follow-Up Studies
- Haplotypes
- Questionnaires
- HEK293 Cells
- Mitogen-Activated Protein Kinase 1/genetics/metabolism
- Adenylate Cyclase/genetics/metabolism
- Luciferases, Renilla
- Receptors, Adrenergic, beta-1/genetics/metabolism
- Receptors, Adrenergic, beta-2/genetics/metabolism
3173: Yang et al. (2012) "Mitochondrial DNA polymorphisms are associated with the longevity in the Guangxi Bama population of China." Mol. Biol. Rep. 39(9):9123-9131 (PubMed)

2 citations in connected databases
- Tags:
- Humans
- Female
- Genotype
- Male
- Longevity/genetics
- Aging/genetics
- Adult
- Child
- Adolescent
- Middle Aged
- Polymorphism, Genetic
- Aged
- Aged, 80 and over
- DNA, Mitochondrial/genetics
- Polymorphism, Single Nucleotide
- China
- Young Adult
- Genetic Loci
- Asian Continental Ancestry Group/ethnology
- Gene Order
3179: Albani et al. (2011) "Insulin-like growth factor 1 receptor polymorphism rs2229765 and circulating interleukin-6 level affect male longevity in a population-based prospective study (Treviso Longeva--TRELONG)." Aging Male 14(4):257-264 (PubMed)

2 citations in connected databases
- Tags:
- Humans
- Female
- Male
- Homozygote
- Longevity/genetics/physiology
- Promoter Regions, Genetic
- Polymorphism, Genetic
- Aged
- Aged, 80 and over
- Receptor, IGF Type 1/genetics
- Sex Factors
- Prospective Studies
- Insulin-Like Growth Factor I/genetics
- Interleukin-6/blood/genetics
- Italy/epidemiology
3195: Tanaka et al. (1998) "Mitochondrial genotype associated with longevity." Lancet 351(9097):185-186 (PubMed)

3 citations in connected databases
- Tags:
- Humans
- Female
- Genotype
- Male
- Longevity/genetics
- Polymerase Chain Reaction
- Middle Aged
- Aged
- Aged, 80 and over
- DNA, Mitochondrial/genetics
- Polymorphism, Restriction Fragment Length
3259: Nojima et al. (2013) "Haploinsufficiency of akt1 prolongs the lifespan of mice." PLoS ONE 8(7):e69178 (PubMed)

5 citations in connected databases
- Tags:
- Animals
- Humans
- Mice
- Mice, Knockout
- Female
- Longevity/genetics
- Phenotype
- Age Factors
- Caenorhabditis elegans/physiology
- Ribosomes/metabolism
- Mitochondria/genetics/metabolism
- Proto-Oncogene Proteins c-akt/genetics
- Haploinsufficiency/genetics