Entries tagged RNA Polymerase II/chemistry/metabolism (67)

  3542: Collette et al. (2014) "Long-term α1B-adrenergic receptor activation shortens lifespan, while α1A-adrenergic receptor stimulation prolongs lifespan in association with decreased cancer incidence." Age (Dordr) 36(4):9675 (PubMed)

  1376: Beglopoulos et al. (2004) "Reduced beta-amyloid production and increased inflammatory responses in presenilin conditional knock-out mice." J. Biol. Chem. 279(45):46907-46914 (PubMed)

  1944: Savage et al. (2002) "Activation of c-Jun N-terminal kinase and p38 in an Alzheimer's disease model is associated with amyloid deposition." J. Neurosci. 22(9):3376-3385 (PubMed)

  2153: Chen et al. (2009) "Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice." Genes Dev. 23(10):1183-1194 (PubMed)

  830: Fischer et al. (1994) "Reversal of spatial memory impairments in aged rats by nerve growth factor and neurotrophins 3 and 4/5 but not by brain-derived neurotrophic factor." Proc. Natl. Acad. Sci. U.S.A. 91(18):8607-8611 (PubMed)

  2969: Cabeza et al. (2004) "Task-independent and task-specific age effects on brain activity during working memory, visual attention and episodic retrieval." Cereb. Cortex 14(4):364-375 (PubMed)

  1422: Cherniske et al. (2004) "Multisystem study of 20 older adults with Williams syndrome." Am. J. Med. Genet. A 131(3):255-264 (PubMed)

  2062: Jaskelioff et al. (2011) "Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice." Nature 469(7328):102-106 (PubMed)

  1607: Dollé et al. (2006) "Increased genomic instability is not a prerequisite for shortened lifespan in DNA repair deficient mice." Mutat. Res. 596(1-2):22-35 (PubMed)

  1610: Payne et al. (2006) "Motor neurone targeting of IGF-1 prevents specific force decline in ageing mouse muscle." J. Physiol. (Lond.) 570(Pt 2):283-294 (PubMed)

  1727: Egan et al. (2003) "The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function." Cell 112(2):257-269 (PubMed)

  1869: Olswang et al. (2002) "A mutation in the peroxisome proliferator-activated receptor gamma-binding site in the gene for the cytosolic form of phosphoenolpyruvate carboxykinase reduces adipose tissue size and fat content in mice." Proc. Natl. Acad. Sci. U.S.A. 99(2):625-630 (PubMed)

  3541: Doze et al. (2011) "Long-term α1A-adrenergic receptor stimulation improves synaptic plasticity, cognitive function, mood, and longevity." Mol. Pharmacol. 80(4):747-758 (PubMed)

  4095: Wan et al. (2013) "Aspirin extends the lifespan of Caenorhabditis elegans via AMPK and DAF-16/FOXO in dietary restriction pathway." Exp. Gerontol. 48(5):499-506 (PubMed)

  15: Henning et al. (1995) "The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH." Cell 82(4):555-564 (PubMed)

  318: Smith et al. (1999) "Age-associated neuronal atrophy occurs in the primate brain and is reversible by growth factor gene therapy." Proc. Natl. Acad. Sci. U.S.A. 96(19):10893-10898 (PubMed)

  2703: Hollenberg et al. (1973) "Renal vascular responses to dopamine: haemodynamic and angiographic observations in normal man." Clin Sci Mol Med 45(6):733-742 (PubMed)

  2826: Dillon et al. (1999) "The optical properties of the anterior segment of the eye: implications for cortical cataract." Exp. Eye Res. 68(6):785-795 (PubMed)

  2941: Boumezbeur et al. (2010) "Altered brain mitochondrial metabolism in healthy aging as assessed by in vivo magnetic resonance spectroscopy." J. Cereb. Blood Flow Metab. 30(1):211-221 (PubMed)

  660: Melov et al. (1998) "A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase." Nat. Genet. 18(2):159-163 (PubMed)