Entries tagged Mitogen-Activated Protein Kinase 8/genetics/physiology (138)

  2048: Wolf et al. (2008) "Klotho: a tumor suppressor and a modulator of the IGF-1 and FGF pathways in human breast cancer." Oncogene 27(56):7094-7105 (PubMed)

  2121: Narala et al. (2008) "SIRT1 acts as a nutrient-sensitive growth suppressor and its loss is associated with increased AMPK and telomerase activity." Mol. Biol. Cell 19(3):1210-1219 (PubMed)

  2322: Loo et al. (2005) "The transcriptional repressor dMnt is a regulator of growth in Drosophila melanogaster." Mol. Cell. Biol. 25(16):7078-7091 (PubMed)

  877: Matsuo et al. (2003) "Control mechanism of the circadian clock for timing of cell division in vivo." Science 302(5643):255-259 (PubMed)

  4206: Fu et al. (2015) "2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling." Cell Metab. 22(3):508-515 (PubMed)

  4222: Latini et al. (2011) "ABI3 ectopic expression reduces in vitro and in vivo cell growth properties while inducing senescence." BMC Cancer 11:11 (PubMed)

  4240: Yee et al. (2012) "TRPM8 ion channel is aberrantly expressed and required for preventing replicative senescence in pancreatic adenocarcinoma: potential role of TRPM8 as a biomarker and target." Cancer Biol. Ther. 13(8):592-599 (PubMed)

  4283: Wang et al. (2015) "Ectopic AP4 expression induces cellular senescence via activation of p53 in long-term confluent retinal pigment epithelial cells." Exp. Cell Res. 339(1):135-146 (PubMed)

  4300: Lu et al. (2014) "Ameliorating replicative senescence of human bone marrow stromal cells by PSMB5 overexpression." Biochem. Biophys. Res. Commun. 443(4):1182-1188 (PubMed)

  4611: Schulz et al. (2007) "Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress." Cell Metab. 6(4):280-293 (PubMed)

  2862: Stolzing et al. (2008) "Age-related changes in human bone marrow-derived mesenchymal stem cells: consequences for cell therapies." Mech. Ageing Dev. 129(3):163-173 (PubMed)

  2070: Wang et al. (2008) "HDAC1 cooperates with C/EBPalpha in the inhibition of liver proliferation in old mice." J. Biol. Chem. 283(38):26169-26178 (PubMed)

  2103: Matheu et al. (2009) "Anti-aging activity of the Ink4/Arf locus." Aging Cell 8(2):152-161 (PubMed)

  2191: Bouwman et al. (2010) "53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers." Nat. Struct. Mol. Biol. 17(6):688-695 (PubMed)

  2221: Bedelbaeva et al. (2010) "Lack of p21 expression links cell cycle control and appendage regeneration in mice." Proc. Natl. Acad. Sci. U.S.A. 107(13):5845-5850 (PubMed)

  2297: Thierbach et al. (2005) "Targeted disruption of hepatic frataxin expression causes impaired mitochondrial function, decreased life span and tumor growth in mice." Hum. Mol. Genet. 14(24):3857-3864 (PubMed)

  2419: Yun et al. (2008) "Proteasomal adaptation to environmental stress links resistance to proteotoxicity with longevity in Caenorhabditis elegans." Proc. Natl. Acad. Sci. U.S.A. 105(19):7094-7099 (PubMed)

  1549: Molofsky et al. (2005) "Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways." Genes Dev. 19(12):1432-1437 (PubMed)

  1915: Dai et al. (2007) "Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis." Cell 130(6):1005-1018 (PubMed)

  4224: Fan et al. (2011) "α-Catulin knockdown induces senescence in cancer cells." Oncogene 30(23):2610-2621 (PubMed)