Entries tagged RNA Polymerase II/antagonists & inhibitors (32)

  3375: Wheatcroft et al. (2007) "IGF-binding protein-2 protects against the development of obesity and insulin resistance." Diabetes 56(2):285-294 (PubMed)

  3859: Anisimov et al. (1982) "Carcinogenesis and aging. IV. Effect of low-molecular-weight factors of thymus, pineal gland and anterior hypothalamus on immunity, tumor incidence and life span of C3H/Sn mice." Mech. Ageing Dev. 19(3):245-258 (PubMed)

  1192: MacLusky et al. (1979) "The development of estrogen receptor systems in the rat brain: perinatal development." Brain Res. 178(1):129-142 (PubMed)

  418: Liou et al. (2003) "Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration." Nature 424(6948):556-561 (PubMed)

  1189: Bigsby et al. (1999) "Protective effects of estrogen in a rat model of age-related cataracts." Proc. Natl. Acad. Sci. U.S.A. 96(16):9328-9332 (PubMed)

  4614: Levitt et al. (1978) "Detection of neoplastic involvement of the mesentery and omentum by computed tomography." AJR Am J Roentgenol 131(5):835-838 (PubMed)

  3230: Jin et al. (2011) "Histone demethylase UTX-1 regulates C. elegans life span by targeting the insulin/IGF-1 signaling pathway." Cell Metab. 14(2):161-172 (PubMed)

  4076: Shukla et al. (2012) "Longevity-promoting effects of 4-hydroxy-E-globularinin in Caenorhabditis elegans." Free Radic. Biol. Med. 53(10):1848-1856 (PubMed)

  4104: Liu et al. (2013) "Reducing sphingolipid synthesis orchestrates global changes to extend yeast lifespan." Aging Cell 12(5):833-841 (PubMed)

  245: Tsujikawa et al. (2003) "Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system." Mol. Endocrinol. 17(12):2393-2403 (PubMed)

  646: Murai et al. (2001) "Early postnatal ataxia and abnormal cerebellar development in mice lacking Xeroderma pigmentosum Group A and Cockayne syndrome Group B DNA repair genes." Proc. Natl. Acad. Sci. U.S.A. 98(23):13379-13384 (PubMed)

  846: Zühlke et al. (2001) "Different types of repeat expansion in the TATA-binding protein gene are associated with a new form of inherited ataxia." Eur. J. Hum. Genet. 9(3):160-164 (PubMed)

  1099: Gueven et al. (2004) "Aprataxin, a novel protein that protects against genotoxic stress." Hum. Mol. Genet. 13(10):1081-1093 (PubMed)

  1195: Heine et al. (2000) "Increased adipose tissue in male and female estrogen receptor-alpha knockout mice." Proc. Natl. Acad. Sci. U.S.A. 97(23):12729-12734 (PubMed)

  1769: Pillai et al. (2005) "Poly(ADP-ribose) polymerase-1-dependent cardiac myocyte cell death during heart failure is mediated by NAD+ depletion and reduced Sir2alpha deacetylase activity." J. Biol. Chem. 280(52):43121-43130 (PubMed)

  2423: Greer et al. (2010) "Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans." Nature 466(7304):383-387 (PubMed)

  2544: Greer et al. (2011) "Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans." Nature 479(7373):365-371 (PubMed)

  2736: Hangartner et al. (1985) "The assessment of cardiac hypertrophy at autopsy." Histopathology 9(12):1295-1306 (PubMed)

  1957: Robinson et al. (2011) "Neocortical and hippocampal amyloid-β and tau measures associate with dementia in the oldest-old." Brain 134(Pt 12):3708-3715 (PubMed)

  62: Pichierri et al. (2000) "Werner's syndrome cell lines are hypersensitive to camptothecin-induced chromosomal damage." Mutat. Res. 456(1-2):45-57 (PubMed)