Entries tagged Adenocarcinoma/genetics (47)

  3727: Binet et al. (2009) "WNT16B is a new marker of cellular senescence that regulates p53 activity and the phosphoinositide 3-kinase/AKT pathway." Cancer Res. 69(24):9183-9191 (PubMed)

  3823: Qian et al. (2008) "DEC1, a basic helix-loop-helix transcription factor and a novel target gene of the p53 family, mediates p53-dependent premature senescence." J. Biol. Chem. 283(5):2896-2905 (PubMed)

  3824: Rao et al. (2007) "MMP-9 short interfering RNA induced senescence resulting in inhibition of medulloblastoma growth via p16(INK4a) and mitogen-activated protein kinase pathway." Cancer Res. 67(10):4956-4964 (PubMed)

  1734: Lim et al. (1997) "Multiple female reproductive failures in cyclooxygenase 2-deficient mice." Cell 91(2):197-208 (PubMed)

  1804: Wang et al. (2006) "Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage." Nat. Cell Biol. 8(9):1025-1031 (PubMed)

  1806: Ford et al. (2005) "Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival." Cancer Res. 65(22):10457-10463 (PubMed)

  2166: Jang et al. (2011) "Anti-proliferative effect of Kv1.3 blockers in A549 human lung adenocarcinoma in vitro and in vivo." Eur. J. Pharmacol. 651(1-3):26-32 (PubMed)

  455: Ye et al. (2001) "The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol." Nature 414(6864):652-656 (PubMed)

  2506: Wang et al. (2008) "Dominant membrane uncoupling by mutant adenine nucleotide translocase in mitochondrial diseases." Hum. Mol. Genet. 17(24):4036-4044 (PubMed)

  1822: Sablina et al. (2005) "The antioxidant function of the p53 tumor suppressor." Nat. Med. 11(12):1306-1313 (PubMed)

  3433: Cai et al. (2005) "Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB." Nat. Med. 11(2):183-190 (PubMed)

  942: Warner et al. (1997) "What does cell death have to do with aging?" J Am Geriatr Soc 45(9):1140-1146 (PubMed)

  273: Chen et al. (2003) "Disruption of ErbB receptor signaling in adult non-myelinating Schwann cells causes progressive sensory loss." Nat. Neurosci. 6(11):1186-1193 (PubMed)

  687: Leroy et al. (1998) "The ubiquitin pathway in Parkinson's disease." Nature 395(6701):451-452 (PubMed)

  3236: Bai et al. (2012) "Drosophila insulin-like peptide-6 (dilp6) expression from fat body extends lifespan and represses secretion of Drosophila insulin-like peptide-2 from the brain." Aging Cell 11(6):978-985 (PubMed)

  3566: Taubert et al. (2006) "A Mediator subunit, MDT-15, integrates regulation of fatty acid metabolism by NHR-49-dependent and -independent pathways in C. elegans." Genes Dev. 20(9):1137-1149 (PubMed)

  3730: López-Vicente et al. (2009) "Regulation of replicative and stress-induced senescence by RSK4, which is down-regulated in human tumors." Clin. Cancer Res. 15(14):4546-4553 (PubMed)

  4037: Lublin et al. (2011) "FDA-approved drugs that protect mammalian neurons from glucose toxicity slow aging dependent on cbp and protect against proteotoxicity." PLoS ONE 6(11):e27762 (PubMed)

  4232: Micutkova et al. (2011) "Insulin-like growth factor binding protein-6 delays replicative senescence of human fibroblasts." Mech. Ageing Dev. 132(10):468-479 (PubMed)

  4252: Lahtela et al. (2013) "A high-content cellular senescence screen identifies candidate tumor suppressors, including EPHA3." Cell Cycle 12(4):625-634 (PubMed)