Entries tagged Dyskeratosis Congenita/enzymology/etiology (93)

  2155: Park et al. (2005) "The haploinsufficient tumor suppressor p18 upregulates p53 via interactions with ATM/ATR." Cell 120(2):209-221 (PubMed)

  2186: Cao et al. (2009) "A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency." Mol. Cell 35(4):534-541 (PubMed)

  2205: Wilhelm et al. (2010) "Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathway." Genes Dev. 24(6):549-560 (PubMed)

  3200: Piaceri et al. (2013) "Ataxia-telangiectasia mutated (ATM) genetic variant in Italian centenarians." Neurol. Sci. 34(4):573-575 (PubMed)

  3725: Calabrese et al. (2009) "SOCS1 links cytokine signaling to p53 and senescence." Mol. Cell 36(5):754-767 (PubMed)

  3808: Zeng et al. (2010) "The histone demethylase RBP2 Is overexpressed in gastric cancer and its inhibition triggers senescence of cancer cells." Gastroenterology 138(3):981-992 (PubMed)

  1563: Xu et al. (1996) "Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma." Genes Dev. 10(19):2411-2422 (PubMed)

  1680: O'Driscoll et al. (2003) "A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome." Nat. Genet. 33(4):497-501 (PubMed)

  1681: Pichierri et al. (2003) "Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during the S phase of the cell cycle." Oncogene 22(10):1491-1500 (PubMed)

  1827: Kim et al. (2006) "Hyperplasia and spontaneous tumor development in the gynecologic system in mice lacking the BRCA1-Delta11 isoform." Mol. Cell. Biol. 26(18):6983-6992 (PubMed)

  1963: Exley et al. (2011) "Premature ageing of the immune system underlies immunodeficiency in ataxia telangiectasia." Clin. Immunol. 140(1):26-36 (PubMed)

  162: Yang et al. (2003) "ATM, ATR and DNA-PK: initiators of the cellular genotoxic stress responses." Carcinogenesis 24(10):1571-1580 (PubMed)

  460: Bornman et al. (1996) "Heat-shock protein 90 and ubiquitin: developmental regulation during myogenesis." Muscle Nerve 19(5):574-580 (PubMed)

  3174: Chen et al. (2010) "A functional single nucleotide polymorphism in promoter of ATM is associated with longevity." Mech. Ageing Dev. 131(10):636-640 (PubMed)

  3309: Baker et al. (2013) "p21 both attenuates and drives senescence and aging in BubR1 progeroid mice." Cell Rep 3(4):1164-1174 (PubMed)

  3360: DiTullio et al. (2002) "53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer." Nat. Cell Biol. 4(12):998-991002 (PubMed)

  3484: Eren et al. (2014) "PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice." Proc. Natl. Acad. Sci. U.S.A. 111(19):7090-7095 (PubMed)

  3569: Armata et al. (2007) "The ataxia telangiectasia-mutated target site Ser18 is required for p53-mediated tumor suppression." Cancer Res. 67(24):11696-11703 (PubMed)

  2079: Guo et al. (2010) "ATM activation by oxidative stress." Science 330(6003):517-521 (PubMed)

  2094: Ruzankina et al. (2009) "Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53." Nat. Genet. 41(10):1144-1149 (PubMed)