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Entries tagged Organoselenium Compounds/pharmacology (762)

835: Martinowich et al. (2003) "DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation." Science 302(5646):890-893 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Mice
- Mice, Inbred BALB C
- Cells, Cultured
- Transfection
- Transcription, Genetic
- Transcription Factors/metabolism
- Gene Expression Regulation
- DNA-Binding Proteins/metabolism
- Promoter Regions, Genetic
- Models, Genetic
- Cyclic AMP Response Element-Binding Protein/metabolism
- Chromatin/metabolism
- Histone Deacetylases/metabolism
- Repressor Proteins/metabolism
- Gene Silencing
- DNA Methylation
- Neuronal Plasticity
- Neurons/metabolism/physiology
- Brain-Derived Neurotrophic Factor/biosynthesis/genetics
- Chromosomal Proteins, Non-Histone
- CpG Islands/physiology
- Methyl-CpG-Binding Protein 2
- Potassium Chloride/pharmacology
- Response Elements
836: Zuccato et al. (2001) "Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease." Science 293(5529):493-498 (PubMed)

2 citations in connected databases
- Tags:
- Animals
- Humans
- Mice
- Apoptosis
- Cells, Cultured
- Mutation
- Transfection
- Mice, Transgenic
- Transcription, Genetic
- Cell Survival
- Promoter Regions, Genetic
- Exons
- Nuclear Proteins/genetics/physiology
- 3T3 Cells
- Neurons/metabolism/pathology
- Nerve Tissue Proteins/genetics/physiology
- Nerve Degeneration
- Nerve Growth Factors/genetics/metabolism
- Brain-Derived Neurotrophic Factor/biosynthesis/genetics/metabolism
- Cerebral Cortex/cytology/metabolism
- Corpus Striatum/cytology/metabolism/pathology
- Hippocampus/cytology/metabolism/pathology
- Huntington Disease/genetics/metabolism/pathology
863: Wu et al. (2003) "Ceramide-induced and age-associated increase in macrophage COX-2 expression is mediated through up-regulation of NF-kappa B activity." J. Biol. Chem. 278(13):10983-10992 (PubMed)

4 citations in connected databases
- Tags:
- Animals
- Mice
- Male
- Mice, Inbred C57BL
- Base Sequence
- Aging/metabolism
- DNA Primers
- NF-kappa B/metabolism
- Gene Expression Regulation, Enzymologic/drug effects
- Ceramides/pharmacology
- Isoenzymes/genetics/metabolism
- Dinoprostone/biosynthesis
- Cyclooxygenase 2
- Macrophages, Peritoneal/drug effects/enzymology
- Prostaglandin-Endoperoxide Synthases/genetics/metabolism
- Up-Regulation/drug effects
866: Loftin et al. (2001) "Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2." Proc. Natl. Acad. Sci. U.S.A. 98(3):1059-1064 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Mice
- Mice, Knockout
- Female
- Genotype
- Male
- Mice, Inbred C57BL
- Mice, Inbred Strains
- Animals, Newborn
- Time Factors
- Genomic Imprinting
- Death
- Isoenzymes/deficiency/genetics/metabolism
- Membrane Proteins
- Cyclooxygenase 2
- Cyclooxygenase 1
- Ductus Arteriosus/pathology
- Ductus Arteriosus, Patent/epidemiology/genetics
- Prostaglandin-Endoperoxide Synthases/deficiency/genetics/metabolism
891: Hisatake et al. (1993) "The p250 subunit of native TATA box-binding factor TFIID is the cell-cycle regulatory protein CCG1." Nature 362(6416):179-181 (PubMed)

2 citations in connected databases
- Tags:
- Animals
- Humans
- Amino Acid Sequence
- Molecular Sequence Data
- Sequence Homology, Amino Acid
- Drosophila
- Molecular Weight
- Electrophoresis, Polyacrylamide Gel
- Blotting, Western
- Repetitive Sequences, Nucleic Acid
- Cell Cycle/physiology
- Macromolecular Substances
- Histone Acetyltransferases
- TATA-Binding Protein Associated Factors
- Transcription Factor TFIID
- Nuclear Proteins/genetics/isolation & purification/metabolism
- DNA-Binding Proteins/genetics/isolation & purification/metabolism
- TATA Box
- Transcription Factors/genetics/isolation & purification/metabolism
900: Godfrey et al. (1993) "GHRH receptor of little mice contains a missense mutation in the extracellular domain that disrupts receptor function." Nat. Genet. 4(3):227-232 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Mice
- Female
- Male
- Mice, Mutant Strains
- Mutation
- Dwarfism/genetics
- Phenotype
- Amino Acid Sequence
- Base Sequence
- Chromosome Mapping
- Molecular Sequence Data
- DNA/genetics
- Growth Hormone/deficiency/secretion
- Receptors, Neuropeptide
- Receptors, Neurotransmitter/genetics
- Receptors, Pituitary Hormone-Regulating Hormone
945: Zervos et al. (1993) "Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites." Cell 72(2):223-232 (PubMed)

3 citations in connected databases
- Tags:
- Humans
- RNA, Messenger/genetics/metabolism
- Tumor Suppressor Proteins
- Transcription Factors
- Transcription, Genetic
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- Molecular Sequence Data
- Sequence Homology, Amino Acid
- HeLa Cells
- Tumor Cells, Cultured
- Binding Sites
- beta-Galactosidase/metabolism
- Open Reading Frames
- Plasmids
- Cell Differentiation/physiology
- Genes, myc
- Oligodeoxyribonucleotides
- DNA-Binding Proteins/chemistry/genetics/metabolism
- Gene Library
- Macromolecular Substances
- Protein Structure, Secondary
- Proto-Oncogene Proteins c-myc/metabolism
- Bacterial Proteins/metabolism
- Escherichia coli/genetics
- Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
- Basic Helix-Loop-Helix Transcription Factors
- Basic-Leucine Zipper Transcription Factors
- DNA, Neoplasm/genetics/isolation & purification
- Leucine Zippers/genetics/physiology
- Serine Endopeptidases
956: La Thangue et al. (1990) "The embryonal carcinoma stem cell Ela-like activity involves a differentiation-regulated transcription factor." Nucleic Acids Res. 18(10):2929-2938 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Humans
- Mice
- DNA-Binding Proteins/genetics/metabolism
- Transcription, Genetic
- Base Sequence
- Cell Line
- Molecular Sequence Data
- DNA/metabolism
- HeLa Cells
- Cell Differentiation
- Transcription Factors/metabolism
- Oncogene Proteins, Viral/genetics/metabolism
- Adenovirus Early Proteins
- Promoter Regions, Genetic
- Embryonal Carcinoma Stem Cells
- Neoplastic Stem Cells/metabolism
1679: Brown and Baltimore (2000) "ATR disruption leads to chromosomal fragmentation and early embryonic lethality." Genes Dev. 14(4):397-402 (PubMed)

5 citations in connected databases
- Tags:
- Animals
- Gene Targeting
- Mice
- Mice, Knockout
- Genotype
- Mice, Inbred C57BL
- Apoptosis/genetics
- Cell Cycle Proteins
- Chromosome Aberrations
- Neoplasms, Experimental/genetics
- DNA Repair/genetics
- Mitosis
- Blastocyst/pathology
- Fetal Death/genetics
- Transcription Factors/physiology
- Gene Expression Regulation, Developmental
- Caspases/metabolism
- Cell Transformation, Neoplastic/genetics
- BRCA2 Protein
- Protein-Serine-Threonine Kinases/deficiency/genetics/physiology
- BRCA1 Protein/physiology
- Neoplasm Proteins/physiology
- Ataxia Telangiectasia Mutated Proteins
95: Murphree and Benedict (1984) "Retinoblastoma: clues to human oncogenesis." Science 223(4640):1028-1033 (PubMed)

1 citation in connected databases
- Tags:
- Humans
- Genotype
- Mutation
- Alleles
- Chromosome Mapping
- Child
- Genes, Recessive
- Eye Neoplasms/genetics
- Retinoblastoma/genetics
- Suppression, Genetic
- Chromosome Deletion
- Adenocarcinoma/genetics
- Chromosomes, Human, 13-15
- Chromosomes, Human, 6-12 and X
- Kidney Neoplasms/genetics
- Neuroblastoma/genetics
- Oncogenes
- Polymorphism, Genetic
- Translocation, Genetic
- Wilms Tumor/genetics
2315: Berman and Kenyon (2006) "Germ-cell loss extends C. elegans life span through regulation of DAF-16 by kri-1 and lipophilic-hormone signaling." Cell 124(5):1055-1068 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Humans
- Insulin-Like Growth Factor I/metabolism
- Longevity/physiology
- Aging/physiology
- Mutation
- Transcription Factors/genetics/metabolism
- Animals, Genetically Modified
- Cell Nucleus/metabolism
- Signal Transduction/physiology
- Genes, Reporter
- Insulin/metabolism
- Models, Animal
- Proto-Oncogene Proteins/genetics/metabolism
- RNA Interference
- Caenorhabditis elegans Proteins/genetics/metabolism
- Germ Cells/physiology
- Membrane Glycoproteins/genetics/metabolism
- Microtubule-Associated Proteins/genetics/metabolism
- Intestines/metabolism
- Receptors, Notch
- PTEN Phosphohydrolase/metabolism
- Caenorhabditis elegans/anatomy & histology/genetics/physiology
- Hormones/chemistry/metabolism
- Urogenital System/metabolism
1500: Brand and Esteves (2005) "Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3." Cell Metab. 2(2):85-93 (PubMed)

3 citations in connected databases
- Tags:
- Animals
- Carrier Proteins/genetics/metabolism
- Aging/physiology
- Oxidative Stress
- Oxidation-Reduction
- Reactive Oxygen Species/metabolism
- Mitochondria/metabolism
- Protein Isoforms/genetics/metabolism
- Ion Channels
- Insulin/secretion
- Fatty Acids/chemistry/metabolism
- Membrane Transport Proteins/genetics/metabolism
- Mitochondrial Proteins/genetics/metabolism
- Obesity/metabolism
- Thermogenesis/physiology
1028: Bray and Cotton (2003) "Variations of the human glucocorticoid receptor gene (NR3C1): pathological and in vitro mutations and polymorphisms." Hum. Mutat. 21(6):557-568 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Humans
- DNA Mutational Analysis
- Molecular Sequence Data
- Mutation/genetics
- Drug Resistance/genetics
- Polymorphism, Genetic/genetics
- Databases, Genetic
- Receptors, Glucocorticoid/genetics
1583: Greer and Brunet (2005) "FOXO transcription factors at the interface between longevity and tumor suppression." Oncogene 24(50):7410-7425 (PubMed)

10 citations in connected databases
- Tags:
- Animals
- Humans
- Aging/physiology
- Longevity
- Cell Transformation, Neoplastic
- Gene Expression Regulation
- Cell Nucleus
- Environment
- Age of Onset
- Mammals/physiology
- Diptera/physiology
- Forkhead Transcription Factors/physiology
- Oligochaeta/physiology
376: Seshadri and Campisi (1990) "Repression of c-fos transcription and an altered genetic program in senescent human fibroblasts." Science 247(4939):205-209 (PubMed)

1 citation in connected databases
- Tags:
- Humans
- Blood
- Cell Division
- Transcription, Genetic
- Cell Line
- Suppression, Genetic
- RNA, Messenger/biosynthesis/genetics
- Fibroblasts/cytology/metabolism
- Proto-Oncogene Proteins/genetics
- Proto-Oncogene Proteins c-fos
- Cell Survival/physiology
- Embryo, Mammalian
- Gene Expression/physiology
- Ornithine Decarboxylase/genetics
- Proto-Oncogene Proteins c-myc
- Proto-Oncogene Proteins p21(ras)
4656: Jeon and Cha (2016) "Anti-aging properties of Ribes fasciculatum in Caenorhabditis elegans." Chin J Nat Med 14(5):335-342 (PubMed)

2 citations in connected databases
- Tags:
- Animals
- Humans
- Reactive Oxygen Species/metabolism
- Caenorhabditis elegans Proteins/genetics/metabolism
- Longevity/drug effects
- Signal Transduction/drug effects
- Oxidative Stress/drug effects
- Aging/drug effects/genetics/metabolism
- Plant Extracts/pharmacology
- Caenorhabditis elegans/drug effects/genetics/growth & development/metabolism
- Ribes/chemistry
2664: Weaver and Chalmers (1966) "Cancellous bone: its strength and changes with aging and an evaluation of some methods for measuring its mineral content." J Bone Joint Surg Am 48(2):289-298 (PubMed)

1 citation in connected databases
- Tags:
- Humans
- Female
- Male
- Aging/physiology
- Adult
- Child
- Adolescent
- Middle Aged
- Aged
- Minerals/metabolism
- Bone and Bones
- Fractures, Bone
- Osteoporosis
- Pathology
367: Chan and Wong (2000) "Expression of epidermal growth factor in transgenic mice causes growth retardation." J. Biol. Chem. 275(49):38693-38698 (PubMed)

1 citation in connected databases
- Tags:
- Animals
- Humans
- Mice
- Body Weight
- Mice, Transgenic
- Promoter Regions, Genetic
- Actins/genetics
- Bone Development
- Epidermal Growth Factor/genetics/physiology
- Growth Disorders/genetics/physiopathology
- Hepatitis, Animal/genetics/pathology
- Insulin-Like Growth Factor Binding Protein 3/blood
- Liver/pathology
- Osteoblasts/pathology/physiology
3310: Chang and Guarente (2013) "SIRT1 mediates central circadian control in the SCN by a mechanism that decays with aging." Cell 153(7):1448-1460 (PubMed)

4 citations in connected databases
- Tags:
- Animals
- Mice
- Male
- Mice, Inbred C57BL
- Aging
- Mice, Transgenic
- Brain/metabolism
- Transcription Factors
- Promoter Regions, Genetic
- Trans-Activators/metabolism
- Neurons/metabolism
- Suprachiasmatic Nucleus/metabolism
- Sirtuin 1/genetics/metabolism
- ARNTL Transcription Factors/genetics
- Circadian Clocks
371: Purdom and Chen (2003) "p66(Shc): at the crossroad of oxidative stress and the genetics of aging." Trends Mol Med 9(5):206-210 (PubMed)

4 citations in connected databases
- Tags:
- Animals
- Mice
- Adaptor Proteins, Signal Transducing
- Proteins/genetics/physiology
- Shc Signaling Adaptor Proteins
- Aging/genetics/physiology
- Oxidative Stress/physiology
- Promoter Regions, Genetic
- DNA Methylation
- Apoptosis/genetics/physiology