Entries tagged Cell Nucleus (33)

  3417: Chu et al. (2013) "Novel locus including FGF21 is associated with dietary macronutrient intake." Hum. Mol. Genet. 22(9):1895-1902 (PubMed)

  2506: Wang et al. (2008) "Dominant membrane uncoupling by mutant adenine nucleotide translocase in mitochondrial diseases." Hum. Mol. Genet. 17(24):4036-4044 (PubMed)

  2507: Almeida et al. (2008) "Isc1p plays a key role in hydrogen peroxide resistance and chronological lifespan through modulation of iron levels and apoptosis." Mol. Biol. Cell 19(3):865-876 (PubMed)

  1658: Esposito et al. (2003) "A novel T608R missense mutation in insulin receptor substrate-1 identified in a subject with type 2 diabetes impairs metabolic insulin signaling." J. Clin. Endocrinol. Metab. 88(4):1468-1475 (PubMed)

  3377: Lin et al. (2011) "A novel mutation in PYCR1 causes an autosomal recessive cutis laxa with premature aging features in a family." Am. J. Med. Genet. A 155A(6):1285-1289 (PubMed)

  3544: Jurk et al. (2014) "Chronic inflammation induces telomere dysfunction and accelerates ageing in mice." Nat Commun 2:4172 (PubMed)

  3881: Howitz et al. (2003) "Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan." Nature 425(6954):191-196 (PubMed)

  4104: Liu et al. (2013) "Reducing sphingolipid synthesis orchestrates global changes to extend yeast lifespan." Aging Cell 12(5):833-841 (PubMed)

  2618: Pan et al. (2011) "Regulation of yeast chronological life span by TORC1 via adaptive mitochondrial ROS signaling." Cell Metab. 13(6):668-678 (PubMed)

  1069: Chang et al. (2004) "Essential role of limiting telomeres in the pathogenesis of Werner syndrome." Nat. Genet. 36(8):877-882 (PubMed)

  1659: Wang et al. (2001) "New amino acid substitutions in the IRS-2 gene in Finnish and Chinese subjects with late-onset type 2 diabetes." Diabetes 50(8):1949-1951 (PubMed)

  1888: Enerbäck et al. (1997) "Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese." Nature 387(6628):90-94 (PubMed)

  2202: Reversade et al. (2009) "Mutations in PYCR1 cause cutis laxa with progeroid features." Nat. Genet. 41(9):1016-1021 (PubMed)

  3145: Beekman et al. (2010) "Genome-wide association study (GWAS)-identified disease risk alleles do not compromise human longevity." Proc. Natl. Acad. Sci. U.S.A. 107(42):18046-18049 (PubMed)

  3401: et al. (2007) "Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels." Science 316(5829):1331-1336 (PubMed)

  1661: Odawara et al. (1989) "Human diabetes associated with a mutation in the tyrosine kinase domain of the insulin receptor." Science 245(4913):66-68 (PubMed)

  1674: Awata et al. (2002) "A common polymorphism in the 5'-untranslated region of the VEGF gene is associated with diabetic retinopathy in type 2 diabetes." Diabetes 51(5):1635-1639 (PubMed)

  493: Marino et al. (1997) "Characterization of tumor necrosis factor-deficient mice." Proc. Natl. Acad. Sci. U.S.A. 94(15):8093-8098 (PubMed)

  3335: Freathy et al. (2010) "Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight." Nat. Genet. 42(5):430-435 (PubMed)

  3024: Bellavia et al. (1999) "C4, BF, C3 allele distribution and complement activity in healthy aged people and centenarians." J. Gerontol. A Biol. Sci. Med. Sci. 54(4):B150-B153 (PubMed)