Entries tagged Drosophila melanogaster/enzymology/genetics (34)

  3855: Comfort et al. (1971) "Effect of ethoxyquin on the longevity of C3H mice." Nature 229(5282):254-255 (PubMed)

  2361: Esposito et al. (1999) "Mitochondrial disease in mouse results in increased oxidative stress." Proc. Natl. Acad. Sci. U.S.A. 96(9):4820-4825 (PubMed)

  2386: Liu et al. (2009) "Reduced expression of alpha-1,2-mannosidase I extends lifespan in Drosophila melanogaster and Caenorhabditis elegans." Aging Cell 8(4):370-379 (PubMed)

  40: Orr et al. (2003) "Effects of overexpression of copper-zinc and manganese superoxide dismutases, catalase, and thioredoxin reductase genes on longevity in Drosophila melanogaster." J. Biol. Chem. 278(29):26418-26422 (PubMed)

  392: Kersten et al. (2000) "Roles of PPARs in health and disease." Nature 405(6785):421-424 (PubMed)

  4515: Tabrez et al. (2017) "Differential alternative splicing coupled to nonsense-mediated decay of mRNA ensures dietary restriction-induced longevity." Nat Commun 8(1):306 (PubMed)

  1439: Tatebayashi et al. (2002) "Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau." Proc. Natl. Acad. Sci. U.S.A. 99(21):13896-13901 (PubMed)

  1441: Ishihara et al. (2001) "Age-dependent induction of congophilic neurofibrillary tau inclusions in tau transgenic mice." Am. J. Pathol. 158(2):555-562 (PubMed)

  2459: Mangerich et al. (2010) "Inflammatory and age-related pathologies in mice with ectopic expression of human PARP-1." Mech. Ageing Dev. 131(6):389-404 (PubMed)

  1727: Egan et al. (2003) "The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function." Cell 112(2):257-269 (PubMed)

  3162: Woo et al. (2012) "The Alu polymorphism of angiotensin I converting enzyme (ACE) and atherosclerosis, incident chronic diseases and mortality in an elderly Chinese population." J Nutr Health Aging 16(3):262-268 (PubMed)

  3544: Jurk et al. (2014) "Chronic inflammation induces telomere dysfunction and accelerates ageing in mice." Nat Commun 2:4172 (PubMed)

  722: De Benedetti et al. (1997) "Interleukin 6 causes growth impairment in transgenic mice through a decrease in insulin-like growth factor-I. A model for stunted growth in children with chronic inflammation." J. Clin. Invest. 99(4):643-650 (PubMed)

  973: Parker et al. (2004) "Decreased expression of Cu-Zn superoxide dismutase 1 in ants with extreme lifespan." Proc. Natl. Acad. Sci. U.S.A. 101(10):3486-3489 (PubMed)

  600: Vekrellis et al. (1997) "Bax promotes neuronal cell death and is downregulated during the development of the nervous system." Development 124(6):1239-1249 (PubMed)

  1785: Maggio et al. (2006) "Interleukin-6 in aging and chronic disease: a magnificent pathway." J. Gerontol. A Biol. Sci. Med. Sci. 61(6):575-584 (PubMed)

  2781: Comijs et al. (2010) "The association between serum cortisol and cognitive decline in older persons." Am J Geriatr Psychiatry 18(1):42-50 (PubMed)

  124: Doyle et al. (2010) "TGFβ signaling in the brain increases with aging and signals to astrocytes and innate immune cells in the weeks after stroke." J Neuroinflammation 7:62 (PubMed)

  2124: Kawauchi et al. (2005) "IL-2 increases human telomerase reverse transcriptase activity transcriptionally and posttranslationally through phosphatidylinositol 3'-kinase/Akt, heat shock protein 90, and mammalian target of rapamycin in transformed NK cells." J. Immunol. 174(9):5261-5269 (PubMed)

  2760: Wagner et al. (2009) "Aging and replicative senescence have related effects on human stem and progenitor cells." PLoS ONE 4(6):e5846 (PubMed)